SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eoy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)
4eoy MICROTUBULE-ASSOCIAT
ED PROTEIN 1 LIGHT
CHAIN 3

(Plasmodium
falciparum)
3 / 3 ARG A  22
TYR A 104
LYS A 108
None
1.07A 1uujB-4eoyA:
undetectable
1uujB-4eoyA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_B_ADNB402_1
(UNCHARACTERIZED
PROTEIN MJ0883)
4eoy MICROTUBULE-ASSOCIAT
ED PROTEIN 1 LIGHT
CHAIN 3

(Plasmodium
falciparum)
5 / 10 PHE A  60
GLY A  58
VAL A  51
LEU A  64
PHE A  49
None
1.29A 3ay0B-4eoyA:
undetectable
3ay0B-4eoyA:
16.51