SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4eq2 INTERFERON GAMMA
RECEPTOR 1
(Gallus
gallus) 		3 / 3 TRP A 204
VAL A 205
PRO A 206
 None
 0.78A 1rg1A-4eq2A:
undetectable		 1rg1A-4eq2A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4eq2 INTERFERON GAMMA
RECEPTOR 1
(Gallus
gallus) 		3 / 3 TRP A 204
VAL A 205
PRO A 206
 None
 0.78A 1rh0A-4eq2A:
undetectable		 1rh0A-4eq2A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 4eq2 INTERFERON GAMMA
RECEPTOR 1
(Gallus
gallus) 		3 / 3 HIS A 121
GLY A 195
ILE A 101
 None
 0.61A 4k50I-4eq2A:
undetectable		 4k50I-4eq2A:
16.52