SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 SER A 147
SER A  15
PHE A  33
ALA A  11
 None
 1.20A 1fxvA-4eqaA:
undetectable
1fxvB-4eqaA:
undetectable		 1fxvA-4eqaA:
20.98
1fxvB-4eqaA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  77
ALA A  74
PHE A  78
VAL A  94
VAL A  95
 None
 0.96A 1ukbA-4eqaA:
undetectable		 1ukbA-4eqaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 HIS A  91
GLY A  86
GLY A  90
ASN A  51
 None
 0.76A 2c49B-4eqaA:
undetectable		 2c49B-4eqaA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A  47
MET A  45
PRO A  44
VAL A 129
 None
 1.12A 2ygoA-4eqaA:
undetectable		 2ygoA-4eqaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ALA A  39
ALA A  38
VAL A  92
MET A  45
LEU A  57
 None
 1.27A 3bszE-4eqaA:
undetectable		 3bszE-4eqaA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A 129
GLN A 121
CYH A 110
 None
 0.68A 5icxA-4eqaA:
undetectable
5icxE-4eqaA:
undetectable		 5icxA-4eqaA:
19.61
5icxE-4eqaA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  91
ALA A 114
SER A 112
GLY A 111
 None
 1.14A 5yodB-4eqaA:
undetectable		 5yodB-4eqaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 HIS A  91
ALA A 114
SER A 112
GLY A 111
 None
 1.16A 5yodD-4eqaA:
undetectable		 5yodD-4eqaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4eqa PUTATIVE
UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 136
TYR A 105
GLY A  98
VAL A  95
 None
 1.06A 6giqL-4eqaA:
undetectable
6giqP-4eqaA:
undetectable
6giqT-4eqaA:
undetectable		 6giqL-4eqaA:
17.07
6giqP-4eqaA:
23.58
6giqT-4eqaA:
19.55