SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4eqk POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		4 / 6 VAL A 463
PRO A 465
GLY A 450
GLU A 452
 None
 0.81A 4dxuA-4eqkA:
undetectable		 4dxuA-4eqkA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 4eqk POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 9 GLN A 383
SER A 405
GLU A 407
ILE A 398
ALA A 397
 None
 1.22A 5entC-4eqkA:
undetectable		 5entC-4eqkA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4eqk POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		3 / 3 ARG A 415
ASN A 448
ASP A 408
 None
 0.85A 5gwxA-4eqkA:
undetectable		 5gwxA-4eqkA:
21.20