SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 4 ILE A 245
LEU A 271
VAL A 107
ILE A 237
 None
 0.91A 1fm6D-4eqmA:
undetectable		 1fm6D-4eqmA:
18.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MUO_A_ADNA1_1
(AURORA-RELATED
KINASE 1)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		6 / 9 LEU A  16
GLY A  17
VAL A  24
ALA A  37
TYR A  89
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.4A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-4.3A)
ANP  A 300 (-4.7A)
 0.64A 1muoA-4eqmA:
12.5		 1muoA-4eqmA:
30.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 7 ASN A 138
HIS A 131
PHE A 152
ILE A 117
 None
 1.32A 1tdnA-4eqmA:
undetectable		 1tdnA-4eqmA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		3 / 3 THR A 186
GLU A  58
HIS A 131
 None
 0.83A 1xwfA-4eqmA:
undetectable		 1xwfA-4eqmA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		3 / 3 THR A 186
GLU A  58
HIS A 131
 None
 0.80A 1xwfB-4eqmA:
undetectable		 1xwfB-4eqmA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		3 / 3 THR A 186
GLU A  58
HIS A 131
 None
 0.84A 1xwfC-4eqmA:
undetectable		 1xwfC-4eqmA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		3 / 3 THR A 186
GLU A  58
HIS A 131
 None
 0.86A 1xwfD-4eqmA:
undetectable		 1xwfD-4eqmA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EVA_A_ADNA498_1
(TAK1 KINASE - TAB1
CHIMERA FUSION
PROTEIN)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		6 / 11 GLY A  17
VAL A  24
ALA A  37
MET A  87
TYR A  89
LEU A 140
 ANP  A 300 ( 4.4A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.3A)
ANP  A 300 (-4.7A)
 0.64A 2evaA-4eqmA:
23.7		 2evaA-4eqmA:
29.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FUM_B_MIXB1539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		8 / 12 LEU A  16
VAL A  24
ALA A  37
MET A  87
TYR A  89
LYS A 135
ASN A 138
ASP A 151
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.3A)
None
None
None
 1.09A 2fumB-4eqmA:
30.3		 2fumB-4eqmA:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		6 / 12 LEU A  16
GLY A  17
VAL A  24
ALA A  37
MET A  87
TYR A  89
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.4A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.3A)
 0.69A 2fumC-4eqmA:
29.9		 2fumC-4eqmA:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FUM_C_MIXC2539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 LEU A  16
VAL A  24
ALA A  37
MET A  87
TYR A  89
THR A  94
ASN A 138
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.3A)
None
None
 0.72A 2fumC-4eqmA:
29.9		 2fumC-4eqmA:
40.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 LEU A  16
VAL A  24
ALA A  37
MET A  87
THR A  94
LYS A 135
ASN A 138
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
None
None
None
 0.84A 2fumD-4eqmA:
30.0		 2fumD-4eqmA:
40.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXK_A_MI1A1125_1
(TYROSINE-PROTEIN
KINASE JAK3)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 LEU A  16
GLY A  17
VAL A  24
ALA A  37
MET A  87
TYR A  89
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.4A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.3A)
ANP  A 300 (-4.7A)
 0.79A 3lxkA-4eqmA:
22.6		 3lxkA-4eqmA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 9 ILE A 195
ILE A 121
VAL A 198
ILE A 149
ILE A 139
 None
 1.17A 3p4wB-4eqmA:
undetectable		 3p4wB-4eqmA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 10 ILE A 195
ILE A 121
VAL A 198
ILE A 149
ILE A 139
 None
 1.17A 3p4wD-4eqmA:
undetectable		 3p4wD-4eqmA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 10 ILE A 195
ILE A 121
VAL A 198
ILE A 149
ILE A 139
 None
 1.17A 3p4wE-4eqmA:
undetectable		 3p4wE-4eqmA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_A_1N1A1_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 LEU A  16
VAL A  24
ALA A  37
VAL A  71
TYR A  89
ILE A  90
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
None
ANP  A 300 (-4.3A)
ANP  A 300 (-4.8A)
ANP  A 300 (-4.7A)
 0.64A 3sxrA-4eqmA:
23.4		 3sxrA-4eqmA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXR_B_1N1B2_1
(CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 LEU A  16
VAL A  24
ALA A  37
VAL A  71
TYR A  89
ILE A  90
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
None
ANP  A 300 (-4.3A)
ANP  A 300 (-4.8A)
ANP  A 300 (-4.7A)
 0.63A 3sxrB-4eqmA:
22.9		 3sxrB-4eqmA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 8 MET A 202
ILE A 117
LEU A 118
VAL A 244
 None
 0.81A 3w1wA-4eqmA:
undetectable		 3w1wA-4eqmA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 9 LEU A  16
LEU A  65
ILE A  70
TYR A  89
ILE A 149
 ANP  A 300 (-4.7A)
None
None
ANP  A 300 (-4.3A)
None
 0.71A 3zosB-4eqmA:
22.3		 3zosB-4eqmA:
26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		6 / 12 LYS A  39
MET A  87
ASP A 133
LYS A 135
ASN A 138
ASP A 151
 ANP  A 300 (-3.1A)
ANP  A 300 (-3.6A)
None
None
None
None
 0.88A 4an2A-4eqmA:
25.3		 4an2A-4eqmA:
26.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 VAL A  24
ILE A  70
TYR A  89
ILE A 149
 ANP  A 300 ( 4.7A)
None
ANP  A 300 (-4.3A)
None
 0.45A 4c8bA-4eqmA:
23.1		 4c8bA-4eqmA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 VAL A  24
ILE A 149
TYR A  89
ILE A 139
 ANP  A 300 ( 4.7A)
None
ANP  A 300 (-4.3A)
None
 0.92A 4c8bA-4eqmA:
23.1		 4c8bA-4eqmA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 8 THR A 114
LEU A 267
VAL A 270
ILE A 237
 None
 0.94A 4l4cB-4eqmA:
undetectable		 4l4cB-4eqmA:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 6 VAL A  24
ALA A  37
LYS A  39
THR A  94
LEU A 140
 ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.1A)
None
ANP  A 300 (-4.7A)
 0.75A 4o0uA-4eqmA:
12.5		 4o0uA-4eqmA:
31.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_1
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 LEU A  16
VAL A  24
LYS A  39
VAL A  71
TYR A  89
LEU A 140
ASP A 151
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 (-3.1A)
None
ANP  A 300 (-4.3A)
ANP  A 300 (-4.7A)
None
 0.99A 4otwA-4eqmA:
24.4		 4otwA-4eqmA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 GLN A  64
LEU A  65
SER A  62
ASP A  29
 None
 1.29A 4qtuD-4eqmA:
undetectable		 4qtuD-4eqmA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 LEU A  16
VAL A  71
TYR A  89
ARG A 132
 ANP  A 300 (-4.7A)
None
ANP  A 300 (-4.3A)
None
 1.07A 4r7iA-4eqmA:
21.4		 4r7iA-4eqmA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 6 LEU A  16
VAL A  24
ILE A  70
ILE A 149
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
None
None
 0.54A 4tyjA-4eqmA:
22.4		 4tyjA-4eqmA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 10 LEU A  16
VAL A  24
LEU A  65
ILE A  70
VAL A  71
TYR A  89
ILE A 149
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
None
None
None
ANP  A 300 (-4.3A)
None
 0.80A 4u0iA-4eqmA:
21.7		 4u0iA-4eqmA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		6 / 9 LEU A  16
VAL A  24
TYR A  89
ARG A 132
LEU A 140
ILE A 149
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 (-4.3A)
None
ANP  A 300 (-4.7A)
None
 1.01A 4v01A-4eqmA:
21.8		 4v01A-4eqmA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 9 LEU A  16
VAL A  24
LYS A  39
TYR A  89
ARG A 132
LEU A 140
ILE A 149
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 (-3.1A)
ANP  A 300 (-4.3A)
None
ANP  A 300 (-4.7A)
None
 1.35A 4v01B-4eqmA:
22.3		 4v01B-4eqmA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_B_ANWB601_0
(RHODOPSIN KINASE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 8 LEU A  16
ALA A  37
MET A  87
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.7A)
 0.52A 4wboB-4eqmA:
22.9		 4wboB-4eqmA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 6 LEU A  16
ALA A  37
MET A  87
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.6A)
ANP  A 300 (-4.7A)
 0.58A 4wboC-4eqmA:
23.0		 4wboC-4eqmA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		3 / 3 ARG A 132
THR A 190
ASP A 191
 None
 0.87A 5g5gA-4eqmA:
undetectable
5g5gB-4eqmA:
undetectable		 5g5gA-4eqmA:
23.13
5g5gB-4eqmA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N3H_A_NCAA401_0
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 10 LEU A  16
VAL A  24
ALA A  37
VAL A  71
MET A  87
TYR A  89
LEU A 140
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
None
ANP  A 300 (-3.6A)
ANP  A 300 (-4.3A)
ANP  A 300 (-4.7A)
 0.74A 5n3hA-4eqmA:
25.3		 5n3hA-4eqmA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		3 / 3 GLU A 273
HIS A 272
ARG A 275
 None
 0.97A 5uunA-4eqmA:
undetectable		 5uunA-4eqmA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_A_1E8A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		7 / 12 GLY A  18
VAL A  24
ALA A  37
LYS A  39
LEU A  85
MET A  87
ASP A 151
 ANP  A 300 ( 3.7A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.1A)
None
ANP  A 300 (-3.6A)
None
 1.17A 5yu9A-4eqmA:
23.3		 5yu9A-4eqmA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_A_1E8A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		8 / 12 LEU A  16
GLY A  17
VAL A  24
ALA A  37
LYS A  39
LEU A  85
MET A  87
ASP A 151
 ANP  A 300 (-4.7A)
ANP  A 300 ( 4.4A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.1A)
None
ANP  A 300 (-3.6A)
None
 0.91A 5yu9A-4eqmA:
23.3		 5yu9A-4eqmA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_B_1E8B1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		6 / 12 GLY A  17
VAL A  24
ALA A  37
LYS A  39
LEU A  85
ASP A 151
 ANP  A 300 ( 4.4A)
ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.1A)
None
None
 0.72A 5yu9B-4eqmA:
23.4		 5yu9B-4eqmA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YU9_C_1E8C1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		5 / 12 VAL A  24
ALA A  37
LYS A  39
LEU A  85
ASP A 151
 ANP  A 300 ( 4.7A)
ANP  A 300 ( 3.8A)
ANP  A 300 (-3.1A)
None
None
 0.75A 5yu9C-4eqmA:
23.0		 5yu9C-4eqmA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 4eqm PROTEIN KINASE
(Staphylococcus
aureus) 		4 / 5 THR A 249
THR A 230
GLN A 239
ASP A 236
 None
 1.25A 6ecxA-4eqmA:
undetectable		 6ecxA-4eqmA:
21.19