SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN
(Streptococcus
phage
TP-J34) 		4 / 5 SER A  86
VAL A  90
SER A  73
VAL A  76
 None
 1.40A 2j9cA-4eqqA:
undetectable
2j9cB-4eqqA:
undetectable
2j9cC-4eqqA:
undetectable		 2j9cA-4eqqA:
21.49
2j9cB-4eqqA:
21.49
2j9cC-4eqqA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN
(Streptococcus
phage
TP-J34) 		3 / 3 THR A  63
ASP A  79
SER A  77
 None
 0.72A 2nxeA-4eqqA:
undetectable		 2nxeA-4eqqA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN
(Streptococcus
phage
TP-J34) 		3 / 3 THR A  63
ASP A  79
SER A  77
 None
 0.77A 2nxeB-4eqqA:
undetectable		 2nxeB-4eqqA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN
(Streptococcus
phage
TP-J34) 		3 / 3 ASP A 110
LYS A 104
LEU A 123
 None
SO4  A 202 (-2.5A)
None
 0.87A 4ptjA-4eqqA:
undetectable		 4ptjA-4eqqA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN
(Streptococcus
phage
TP-J34) 		3 / 3 ALA A 137
ASN A 140
LEU A 141
 None
 0.36A 5i1oC-4eqqA:
undetectable		 5i1oC-4eqqA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4eqq PUTATIVE HOST CELL
SURFACE-EXPOSED
LIPOPROTEIN
(Streptococcus
phage
TP-J34) 		3 / 3 ALA A 137
ASN A 140
LEU A 141
 None
 0.35A 5i1pA-4eqqA:
undetectable		 5i1pA-4eqqA:
16.19