SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		3 / 3 VAL A 247
ALA A 246
HIS A 165
 None
 0.76A 1q23G-4eqyA:
undetectable		 1q23G-4eqyA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 12 GLY A 163
SER A 166
VAL A 130
LEU A 174
LEU A 132
 None
 0.98A 1ya4C-4eqyA:
undetectable		 1ya4C-4eqyA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		4 / 6 TYR A 220
ASP A 177
PHE A 253
ARG A 161
 None
 1.18A 2a3bB-4eqyA:
undetectable		 2a3bB-4eqyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		3 / 3 ARG A 161
ASP A 146
ASP A 110
 None
 0.84A 2ejtA-4eqyA:
undetectable		 2ejtA-4eqyA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		4 / 7 TYR A  74
GLY A  98
THR A  97
ASP A 123
 None
 1.08A 2g70B-4eqyA:
undetectable		 2g70B-4eqyA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 9 ALA A 173
VAL A 156
GLY A 151
ILE A 162
ALA A 189
 None
 0.99A 2z0yA-4eqyA:
undetectable		 2z0yA-4eqyA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 9 VAL A 156
GLY A 170
GLY A 151
ILE A 162
ALA A 189
 None
 0.92A 2z0yB-4eqyA:
undetectable		 2z0yB-4eqyA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 12 ASN A  87
ALA A 148
VAL A 150
ILE A  83
THR A 106
 None
 1.11A 3czhA-4eqyA:
undetectable		 3czhA-4eqyA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 GLY A 243
GLY A 241
ASP A 244
ALA A 237
ALA A 249
 None
 1.11A 3g88A-4eqyA:
undetectable		 3g88A-4eqyA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 HIS A 141
THR A  51
THR A 106
THR A  99
GLY A  67
 None
 1.47A 4qvlV-4eqyA:
undetectable
4qvlb-4eqyA:
undetectable		 4qvlV-4eqyA:
23.75
4qvlb-4eqyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 HIS A 141
THR A  51
THR A 106
THR A  99
GLY A  67
 None
 1.46A 4qvlH-4eqyA:
undetectable
4qvlN-4eqyA:
undetectable		 4qvlH-4eqyA:
23.75
4qvlN-4eqyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 HIS A 141
THR A  51
THR A 106
THR A  99
GLY A  67
 None
 1.46A 4qw1V-4eqyA:
undetectable
4qw1b-4eqyA:
undetectable		 4qw1V-4eqyA:
23.75
4qw1b-4eqyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 HIS A 141
THR A  51
THR A 106
THR A  99
GLY A  67
 None
 1.46A 4qw1H-4eqyA:
undetectable
4qw1N-4eqyA:
undetectable		 4qw1H-4eqyA:
23.75
4qw1N-4eqyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 HIS A 141
THR A  51
THR A 106
THR A  99
GLY A  67
 None
 1.43A 5bxnV-4eqyA:
undetectable
5bxnb-4eqyA:
undetectable		 5bxnV-4eqyA:
25.99
5bxnb-4eqyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eqy ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Burkholderia
thailandensis) 		5 / 11 HIS A 141
THR A  51
THR A 106
THR A  99
GLY A  67
 None
 1.44A 5bxnH-4eqyA:
undetectable
5bxnN-4eqyA:
undetectable		 5bxnH-4eqyA:
25.99
5bxnN-4eqyA:
20.57