SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4erc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	4erc	DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 (Homo sapiens)	4 / 5	LEU A 16 TYR A 109 LEU A 110 ARG A 114	None	1.33A	4em2A-4ercA: undetectable	4em2A-4ercA: 16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4F_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	4erc	DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 (Homo sapiens)	4 / 7	LEU A 39 PRO A 47 LEU A 56 TYR A 28	None	1.06A	4z4fA-4ercA: 2.6	4z4fA-4ercA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OHH_A_ACTA307_0 (CARBONIC ANHYDRASE 13)	4erc	DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 (Homo sapiens)	4 / 5	HIS A 59 HIS A 38 VAL A 91 LEU A 56	None	1.35A	5ohhA-4ercA: undetectable	5ohhA-4ercA: 18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5T7B_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	4erc	DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 (Homo sapiens)	4 / 7	LEU A 39 PRO A 47 LEU A 56 TYR A 28	None	1.01A	5t7bA-4ercA: undetectable	5t7bA-4ercA: 10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA609_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	4erc	DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 (Homo sapiens)	3 / 3	HIS A 38 HIS A 59 ARG A 76	None	0.78A	6b58A-4ercA: undetectable	6b58A-4ercA: 14.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","4erc","DUAL SPECIFICITY PROTEIN PHOSPHATASE 23","Homo sapiens",4,"LEU A  16;TYR A 109;LEU A 110;ARG A 114","None","1.33A","4em2A-4ercA:undetectable","4em2A-4ercA:16.85"],["4Z4F_A_IPHA902_0","PROTEIN ARGONAUTE-2","4erc","DUAL SPECIFICITY PROTEIN PHOSPHATASE 23","Homo sapiens",4,"LEU A  39;PRO A  47;LEU A  56;TYR A  28","None","1.06A","4z4fA-4ercA:2.6","4z4fA-4ercA:10.40"],["5OHH_A_ACTA307_0","CARBONIC ANHYDRASE 13","4erc","DUAL SPECIFICITY PROTEIN PHOSPHATASE 23","Homo sapiens",4,"HIS A  59;HIS A  38;VAL A  91;LEU A  56","None","1.35A","5ohhA-4ercA:undetectable","5ohhA-4ercA:18.99"],["5T7B_A_IPHA902_0","PROTEIN ARGONAUTE-2","4erc","DUAL SPECIFICITY PROTEIN PHOSPHATASE 23","Homo sapiens",4,"LEU A  39;PRO A  47;LEU A  56;TYR A  28","None","1.01A","5t7bA-4ercA:undetectable","5t7bA-4ercA:10.40"],["6B58_A_ACTA609_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","4erc","DUAL SPECIFICITY PROTEIN PHOSPHATASE 23","Homo sapiens",3,"HIS A  38;HIS A  59;ARG A  76","None","0.78A","6b58A-4ercA:undetectable","6b58A-4ercA:14.91"]]