SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4es4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		4 / 6 LEU A 121
TYR A 118
ILE A 114
GLY A 129
 None
 0.93A 2du8A-4es4A:
undetectable		 2du8A-4es4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		4 / 6 LEU A 121
TYR A 118
ILE A 114
GLY A 129
 None
 0.95A 2du8B-4es4A:
undetectable		 2du8B-4es4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		3 / 3 PHE A 178
PHE A 213
PHE A 215
 None
 0.62A 2od9A-4es4A:
undetectable		 2od9A-4es4A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		3 / 3 PHE A 178
PHE A 213
PHE A 215
 None
 0.62A 2qqgA-4es4A:
undetectable		 2qqgA-4es4A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		3 / 3 CYH A  71
PHE A  74
PHE A  75
 None
 0.65A 3cr5X-4es4A:
undetectable		 3cr5X-4es4A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		3 / 3 GLU A 179
PHE A 213
GLN A 209
 None
 0.84A 3r55A-4es4A:
undetectable		 3r55A-4es4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		4 / 7 PHE A 213
ILE A 210
ASP A  20
PHE A 215
 None
 0.81A 5h3aA-4es4A:
undetectable		 5h3aA-4es4A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 4es4 PUTATIVE CYCLIC
DI-GMP REGULATOR
CDGR
(Escherichia
coli) 		4 / 7 PHE A 213
ILE A 210
ASP A  20
PHE A 215
 None
 0.78A 5h3aB-4es4A:
undetectable		 5h3aB-4es4A:
20.74