SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4es7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 6 TYR A 104
VAL A  97
VAL A 141
ASP A 138
 None
 1.06A 1dz4A-4es7A:
undetectable		 1dz4A-4es7A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 PHE A   9
ILE A  11
VAL A  96
ALA A 105
LYS A 123
 None
 0.75A 1epbA-4es7A:
19.5		 1epbA-4es7A:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 PHE A   9
TRP A  18
VAL A  96
ALA A 105
LYS A 123
 None
 0.57A 1epbA-4es7A:
19.5		 1epbA-4es7A:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 PHE A   9
ILE A  11
VAL A  96
ALA A 105
LYS A 123
 None
 0.90A 1epbB-4es7A:
19.6		 1epbB-4es7A:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 PHE A   9
TRP A  18
VAL A  96
ALA A 105
LYS A 123
 None
 0.74A 1epbB-4es7A:
19.6		 1epbB-4es7A:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 GLY A  24
THR A 155
ALA A  22
ALA A 143
PHE A 139
 None
 0.99A 2gluB-4es7A:
undetectable		 2gluB-4es7A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 THR A  26
THR A 155
ALA A  22
ALA A 143
PHE A 139
 None
 0.87A 2gluB-4es7A:
undetectable		 2gluB-4es7A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.44A 3ag1J-4es7A:
undetectable		 3ag1J-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.45A 3ag4J-4es7A:
undetectable		 3ag4J-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		3 / 3 LYS A  62
ARG A  36
LYS A 123
 None
 1.34A 3okxA-4es7A:
undetectable		 3okxA-4es7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 6 TYR A 104
VAL A  97
VAL A 141
ASP A 138
 None
 1.11A 4ek1A-4es7A:
undetectable		 4ek1A-4es7A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 12 MET A 156
ILE A  23
VAL A  39
GLY A  16
TYR A  72
 None
 1.13A 5igiA-4es7A:
undetectable		 5igiA-4es7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		5 / 10 GLY A  24
LEU A 136
ILE A 106
LEU A 124
ALA A  22
 None
 0.97A 5vm8B-4es7A:
undetectable		 5vm8B-4es7A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.39A 5wauJ-4es7A:
undetectable		 5wauJ-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.38A 5x19J-4es7A:
undetectable		 5x19J-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.41A 5x1bJ-4es7A:
undetectable		 5x1bJ-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.39A 5x1bW-4es7A:
undetectable		 5x1bW-4es7A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4es7 PROTEIN AMBP
(Homo
sapiens) 		4 / 5 TYR A  72
MET A  55
THR A  56
LEU A  42
 None
 1.40A 5x1fW-4es7A:
undetectable		 5x1fW-4es7A:
16.11