SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4esb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 4esb TRANSCRIPTIONAL
REGULATOR, PADR
FAMILY
(Bacillus
cereus) 		5 / 12 TYR A  46
TYR A  24
TYR A  73
LEU A  28
ILE A  18
 None
SO4  A 201 (-4.7A)
GOL  A 202 (-4.2A)
None
None
 1.21A 1fmlA-4esbA:
undetectable		 1fmlA-4esbA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4esb TRANSCRIPTIONAL
REGULATOR, PADR
FAMILY
(Bacillus
cereus) 		5 / 9 TYR A  26
GLY A  43
ASN A  33
VAL A  40
ILE A  45
 None
 1.29A 6giqA-4esbA:
undetectable
6giqE-4esbA:
undetectable
6giqI-4esbA:
undetectable		 6giqA-4esbA:
15.89
6giqE-4esbA:
18.69
6giqI-4esbA:
17.54