SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4esp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_A_ACTA653_0 (ACETYL-COENZYME A SYNTHETASE)	4esp	PROFILIN (Arachis hypogaea)	4 / 5	VAL A 92 THR A 93 VAL A 82 GLY A 77	None None None EDO A 205 ( 3.6A)	1.14A	2p2fA-4espA: undetectable	2p2fA-4espA: 11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_B_ACTB653_0 (ACETYL-COENZYME A SYNTHETASE)	4esp	PROFILIN (Arachis hypogaea)	4 / 4	VAL A 92 THR A 93 VAL A 82 GLY A 77	None None None EDO A 205 ( 3.6A)	1.10A	2p2fB-4espA: undetectable	2p2fB-4espA: 11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA5_A_06XA502_1 (CYTOCHROME P450 2B6)	4esp	PROFILIN (Arachis hypogaea)	5 / 11	LEU A 101 GLU A 46 LEU A 65 PRO A 40 PHE A 39	None	1.30A	3ua5A-4espA: undetectable	3ua5A-4espA: 14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TVT_A_ASCA302_0 (THAUMATIN-1)	4esp	PROFILIN (Arachis hypogaea)	3 / 3	ARG A 84 GLN A 76 GLU A 78	None	0.92A	4tvtA-4espA: undetectable	4tvtA-4espA: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA812_0 (GEPHYRIN)	4esp	PROFILIN (Arachis hypogaea)	4 / 6	GLU A 46 LYS A 43 PHE A 42 PRO A 40	None None EDO A 207 (-3.8A) None	1.17A	6fgdA-4espA: undetectable	6fgdA-4espA: 15.07

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2P2F_A_ACTA653_0","ACETYL-COENZYME A SYNTHETASE","4esp","PROFILIN","Arachis hypogaea",4,"VAL A  92;THR A  93;VAL A  82;GLY A  77","None;None;None;EDO A 205 ( 3.6A)","1.14A","2p2fA-4espA:undetectable","2p2fA-4espA:11.98"],["2P2F_B_ACTB653_0","ACETYL-COENZYME A SYNTHETASE","4esp","PROFILIN","Arachis hypogaea",4,"VAL A  92;THR A  93;VAL A  82;GLY A  77","None;None;None;EDO A 205 ( 3.6A)","1.10A","2p2fB-4espA:undetectable","2p2fB-4espA:11.98"],["3UA5_A_06XA502_1","CYTOCHROME P450 2B6","4esp","PROFILIN","Arachis hypogaea",5,"LEU A 101;GLU A  46;LEU A  65;PRO A  40;PHE A  39","None","1.30A","3ua5A-4espA:undetectable","3ua5A-4espA:14.74"],["4TVT_A_ASCA302_0","THAUMATIN-1","4esp","PROFILIN","Arachis hypogaea",3,"ARG A  84;GLN A  76;GLU A  78","None","0.92A","4tvtA-4espA:undetectable","4tvtA-4espA:19.89"],["6FGD_A_ACTA812_0","GEPHYRIN","4esp","PROFILIN","Arachis hypogaea",4,"GLU A  46;LYS A  43;PHE A  42;PRO A  40","None;None;EDO A 207 (-3.8A);None","1.17A","6fgdA-4espA:undetectable","6fgdA-4espA:15.07"]]