SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4esy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 10 VAL A 357
GLU A 328
GLY A 358
PRO A 409
THR A 412
 None
 1.45A 3bjwD-4esyA:
undetectable		 3bjwD-4esyA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 ILE A 359
THR A 361
ASP A 364
THR A 407
PRO A 435
 None
 0.89A 3kpbA-4esyA:
15.5		 3kpbA-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 ILE A 359
THR A 361
ASP A 364
THR A 407
ILE A 431
 None
 1.08A 3kpbC-4esyA:
15.2		 3kpbC-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 ILE A 359
THR A 361
ASP A 364
THR A 407
PRO A 435
 None
 0.87A 3kpbC-4esyA:
15.2		 3kpbC-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 THR A 447
ASP A 450
LYS A 453
ILE A 344
PRO A 348
 CL  A 502 (-4.1A)
None
None
None
None
 1.09A 3kpbC-4esyA:
15.2		 3kpbC-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 THR A 447
ASP A 450
LYS A 453
ILE A 344
PRO A 348
 CL  A 502 (-4.1A)
None
None
None
None
 1.25A 3kpbC-4esyA:
15.2		 3kpbC-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_D_SAMD1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 10 ILE A 359
THR A 361
ASP A 364
THR A 407
ILE A 431
 None
 1.09A 3kpbD-4esyA:
14.9		 3kpbD-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 11 ILE A 359
ASP A 364
THR A 407
ILE A 431
PRO A 435
 None
 1.24A 3kpcA-4esyA:
14.0		 3kpcA-4esyA:
29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 11 ILE A 359
THR A 361
ASP A 364
THR A 407
ILE A 431
 None
 1.03A 3kpcA-4esyA:
14.0		 3kpcA-4esyA:
29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 ILE A 359
THR A 361
ASP A 364
THR A 407
ILE A 431
 None
 1.04A 3kpdB-4esyA:
14.4		 3kpdB-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 ILE A 359
THR A 361
ASP A 364
THR A 407
ILE A 431
 None
 1.08A 3kpdC-4esyA:
13.7		 3kpdC-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 12 ILE A 359
THR A 361
ASP A 364
THR A 407
PRO A 435
 None
 0.88A 3kpdC-4esyA:
13.7		 3kpdC-4esyA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4esy CBS DOMAIN
CONTAINING MEMBRANE
PROTEIN
(Sphaerobacter
thermophilus) 		5 / 11 SER A 321
ALA A 347
PRO A 348
THR A 447
ASP A 450
 None
None
None
CL  A 502 (-4.1A)
None
 0.78A 4uuuB-4esyA:
14.2		 4uuuB-4esyA:
22.65