SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4et7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4et7 EPHRIN TYPE-A
RECEPTOR 5
(Homo
sapiens) 		5 / 10 ASN A 111
VAL A 101
TYR A  99
GLY A  82
TRP A  75
 None
 1.28A 3lp1A-4et7A:
undetectable		 3lp1A-4et7A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4et7 EPHRIN TYPE-A
RECEPTOR 5
(Homo
sapiens) 		4 / 5 ILE A 118
LEU A 113
HIS A  97
VAL A  69
 None
 1.16A 5jmnB-4et7A:
undetectable		 5jmnB-4et7A:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 4et7 EPHRIN TYPE-A
RECEPTOR 5
(Homo
sapiens) 		4 / 4 ASN A 165
LEU A 114
SER A 116
LEU A 212
 None
 1.36A 5kb5A-4et7A:
undetectable		 5kb5A-4et7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 4et7 EPHRIN TYPE-A
RECEPTOR 5
(Homo
sapiens) 		5 / 11 MET A 153
ILE A 177
VAL A 226
LEU A 134
THR A 133
 None
 1.47A 5tiyA-4et7A:
undetectable		 5tiyA-4et7A:
22.08