SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4etm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		4 / 8 SER A  39
ILE A  85
LEU A   5
ASP A 113
 K  A 203 (-3.5A)
None
None
None
 0.90A 1jg4A-4etmA:
undetectable		 1jg4A-4etmA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		4 / 5 ASP A 122
GLU A 134
THR A 129
SER A  95
 None
 1.39A 3p2kC-4etmA:
2.5		 3p2kC-4etmA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		4 / 6 ILE A 150
TYR A  84
ASP A 113
THR A 105
 None
 1.07A 3q70A-4etmA:
undetectable		 3q70A-4etmA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		4 / 5 PHE A   6
TYR A 114
LEU A   9
ARG A 110
 None
None
PO4  A 201 (-4.2A)
None
 1.17A 3sudD-4etmA:
undetectable		 3sudD-4etmA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		3 / 3 ASP A 125
GLY A  10
TYR A 128
 PO4  A 201 (-2.9A)
PO4  A 201 (-3.4A)
None
 0.69A 3w9tC-4etmA:
undetectable		 3w9tC-4etmA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		3 / 3 ASP A 125
GLY A  10
TYR A 128
 PO4  A 201 (-2.9A)
PO4  A 201 (-3.4A)
None
 0.68A 3w9tG-4etmA:
undetectable		 3w9tG-4etmA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		5 / 12 ILE A  42
GLY A  10
ALA A  40
ALA A  18
MET A  88
 None
PO4  A 201 (-3.4A)
None
None
None
 0.95A 4kicB-4etmA:
undetectable		 4kicB-4etmA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		3 / 3 ASP A  89
TRP A  45
SER A  95
 None
 0.90A 4lrhB-4etmA:
undetectable		 4lrhB-4etmA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		3 / 3 ASP A  89
TRP A  45
SER A  95
 None
 0.88A 4lrhF-4etmA:
undetectable		 4lrhF-4etmA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 4etm LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YFKJ
(Bacillus
subtilis) 		4 / 7 SER A  39
ALA A  18
ILE A  58
LEU A  59
 K  A 203 (-3.5A)
None
None
None
 1.02A 5te8A-4etmA:
undetectable		 5te8A-4etmA:
16.99