SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4etn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 4etn LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		4 / 4 THR A 130
LEU A 134
LEU A 141
GLN A 144
 None
 0.93A 1fbmA-4etnA:
undetectable		 1fbmA-4etnA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4etn LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		4 / 7 ILE A  90
LEU A  69
GLY A  38
PHE A  40
 None
 0.89A 1rtsB-4etnA:
undetectable		 1rtsB-4etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4etn LOW MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		5 / 12 ALA A  19
LEU A  55
ALA A  51
THR A  48
GLY A  45
 None
 1.07A 2ve3A-4etnA:
undetectable		 2ve3A-4etnA:
18.31