SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eto'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		4 / 7 ILE A  82
LEU A  79
PHE A  78
THR A  39
 None
 1.08A 2zxwN-4etoA:
undetectable
2zxwW-4etoA:
undetectable		 2zxwN-4etoA:
9.45
2zxwW-4etoA:
22.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		3 / 3 GLU A   6
LEU A   9
ASP A  10
 None
 0.28A 3ko0A-4etoA:
16.8		 3ko0A-4etoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		4 / 6 LEU A  42
ILE A  82
CYH A  86
PHE A  89
 None
 0.68A 3ko0B-4etoA:
16.8		 3ko0B-4etoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		4 / 6 LEU A  42
ILE A  82
CYH A  86
PHE A  89
 None
 0.63A 3ko0S-4etoA:
16.7		 3ko0S-4etoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		3 / 3 GLU A   6
LEU A   9
ASP A  10
 None
 0.35A 3ko0T-4etoA:
16.6		 3ko0T-4etoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVV_A_CPFA1081_1
(APOLIPOPROTEIN(A))		 4eto PROTEIN S100-A4
(Homo
sapiens) 		5 / 9 SER A  14
THR A  15
TYR A  75
LEU A  79
PHE A  78
 None
 1.11A 4bvvA-4etoA:
undetectable		 4bvvA-4etoA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		4 / 6 ILE A  82
LEU A  79
PHE A  78
THR A  39
 None
 1.03A 5b1aN-4etoA:
undetectable
5b1aW-4etoA:
undetectable		 5b1aN-4etoA:
9.45
5b1aW-4etoA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 4eto PROTEIN S100-A4
(Homo
sapiens) 		5 / 12 GLY A  21
SER A  20
LYS A  26
ASN A  30
GLU A  33
 CA  A 101 ( 4.9A)
None
None
None
CA  A 101 (-2.2A)
 1.24A 5nwvA-4etoA:
undetectable		 5nwvA-4etoA:
18.39