SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4etv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)
4etv RYANODINE RECEPTOR 2
(Mus
musculus)
3 / 3 TYR A2873
ARG A2885
LYS A2881
None
1.33A 4wq5B-4etvA:
undetectable
4wq5B-4etvA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)
4etv RYANODINE RECEPTOR 2
(Mus
musculus)
3 / 3 LYS A2757
PRO A2758
LYS A2760
None
0.81A 5y9yA-4etvA:
undetectable
5y9yA-4etvA:
20.00