SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 8 SER A 395
GLY A 388
HIS A 113
ALA A 393
 None
COA  A2598 ( 4.4A)
None
None
 0.81A 1gtnE-4eudA:
undetectable
1gtnF-4eudA:
undetectable		 1gtnE-4eudA:
9.56
1gtnF-4eudA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 5 PRO A  91
GLY A 115
ASN A 347
GLY A 388
 None
None
None
COA  A2598 ( 4.4A)
 0.99A 1zlqA-4eudA:
0.7		 1zlqA-4eudA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 7 SER A 445
THR A 482
PRO A 483
GLY A 370
 None
 0.98A 2ddwB-4eudA:
undetectable		 2ddwB-4eudA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 7 ARG A 222
GLU A  43
ALA A 219
ALA A  20
 None
 0.87A 2ejfA-4eudA:
undetectable		 2ejfA-4eudA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 5 SER A 315
GLY A 152
HIS A 113
ASP A 344
 None
 1.15A 2oxtB-4eudA:
undetectable		 2oxtB-4eudA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 ALA A  38
ALA A 230
VAL A 270
GLY A 269
GLN A 267
 None
None
None
COA  A2598 (-3.6A)
COA  A2598 (-4.7A)
 1.17A 2ve3B-4eudA:
undetectable		 2ve3B-4eudA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 7 LEU A 160
GLY A 189
ARG A 193
PHE A 157
 None
 0.87A 2wq5A-4eudA:
undetectable		 2wq5A-4eudA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 11 VAL A 273
LEU A 246
SER A 268
MET A 360
ILE A 400
 None
 1.24A 2zbzA-4eudA:
undetectable		 2zbzA-4eudA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 0.93A 3elwA-4eudA:
undetectable		 3elwA-4eudA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 0.90A 3embA-4eudA:
undetectable		 3embA-4eudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 0.94A 3gczA-4eudA:
undetectable		 3gczA-4eudA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A 350
GLY A 356
ARG A 394
ALA A 393
ASP A 428
 None
 0.99A 3keeA-4eudA:
undetectable		 3keeA-4eudA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A 350
GLY A 356
ARG A 394
ALA A 393
ASP A 428
 None
 1.01A 3keeC-4eudA:
undetectable		 3keeC-4eudA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A 350
GLY A 356
ARG A 394
ALA A 393
ASP A 428
 None
 1.07A 3keeD-4eudA:
undetectable		 3keeD-4eudA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 4 GLY A  34
TYR A  40
GLY A  37
ASP A 227
 None
 1.24A 3kl3A-4eudA:
undetectable		 3kl3A-4eudA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 7 LEU A 114
SER A 154
ASN A 153
THR A 148
 None
 1.06A 3lm8B-4eudA:
2.9
3lm8D-4eudA:
2.7		 3lm8B-4eudA:
18.84
3lm8D-4eudA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 6 THR A  68
SER A 316
ASP A  95
THR A  32
 None
 1.05A 3q70A-4eudA:
undetectable		 3q70A-4eudA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 PHE A 250
HIS A 252
ALA A 243
GLY A 244
MET A 360
 None
 1.23A 3v3oB-4eudA:
undetectable		 3v3oB-4eudA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 4 ASN A 173
SER A 318
LEU A 319
THR A 137
 None
 1.48A 4an2A-4eudA:
undetectable		 4an2A-4eudA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		3 / 3 TYR A 292
ARG A 341
SER A 346
 None
 1.13A 4dr2I-4eudA:
undetectable
4dr2J-4eudA:
undetectable		 4dr2I-4eudA:
14.00
4dr2J-4eudA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 6 PHE A  35
ALA A  70
GLY A 115
VAL A 117
 None
 1.03A 4dubA-4eudA:
undetectable		 4dubA-4eudA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 11 GLY A 152
ASN A 153
ALA A 121
PRO A 147
ILE A 182
 None
 1.49A 4j4vA-4eudA:
undetectable		 4j4vA-4eudA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 11 ASP A 391
PRO A 265
SER A 395
SER A 396
GLY A 356
 None
 1.27A 4mmaA-4eudA:
undetectable		 4mmaA-4eudA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 LEU A 266
GLY A 291
LEU A 304
MET A 309
ILE A 339
 None
 1.34A 4okbA-4eudA:
undetectable		 4okbA-4eudA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		6 / 12 ARG A 449
LEU A 441
ASP A 440
ILE A 400
ILE A 358
ILE A 431
 None
 1.48A 4q1xB-4eudA:
undetectable		 4q1xB-4eudA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 7 LEU A 133
THR A 223
ALA A  17
LEU A  23
 None
 0.71A 4ubsA-4eudA:
undetectable		 4ubsA-4eudA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 10 GLY A  39
THR A 137
HIS A 180
LEU A 176
LEU A 210
 None
 1.36A 4yb6C-4eudA:
undetectable
4yb6F-4eudA:
undetectable		 4yb6C-4eudA:
21.05
4yb6F-4eudA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 10 HIS A 180
LEU A 176
LEU A 210
GLY A  39
THR A 137
 None
 1.36A 4yb6D-4eudA:
undetectable
4yb6E-4eudA:
undetectable		 4yb6D-4eudA:
21.05
4yb6E-4eudA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 ILE A 453
ALA A 450
LEU A 466
MET A 363
PHE A 432
 None
 1.17A 4zo1X-4eudA:
undetectable		 4zo1X-4eudA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 1.00A 5ehiA-4eudA:
undetectable		 5ehiA-4eudA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 1.02A 5ehiC-4eudA:
undetectable		 5ehiC-4eudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 0.97A 5eiwA-4eudA:
undetectable		 5eiwA-4eudA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 0.99A 5ekxA-4eudA:
undetectable		 5ekxA-4eudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 GLY A  73
GLY A  69
GLY A  34
GLY A  37
VAL A 117
 None
 0.96A 5njvC-4eudA:
undetectable		 5njvC-4eudA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 12 LEU A 246
GLY A 251
VAL A 254
LEU A 398
ARG A 442
 None
 1.13A 5uc1A-4eudA:
undetectable		 5uc1A-4eudA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		3 / 3 ARG A 354
ARG A 341
ARG A 200
 CL  A 516 ( 3.8A)
None
None
 0.72A 5vcgA-4eudA:
undetectable		 5vcgA-4eudA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 5 LEU A 438
PHE A 432
LEU A 246
PHE A 250
 None
 0.93A 5x1fC-4eudA:
undetectable
5x1fJ-4eudA:
undetectable		 5x1fC-4eudA:
17.99
5x1fJ-4eudA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 8 ASP A 181
ILE A 182
ARG A 341
ASN A 153
 None
 1.04A 6hisA-4eudA:
undetectable
6hisB-4eudA:
undetectable		 6hisA-4eudA:
9.36
6hisB-4eudA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 8 ASP A 181
ILE A 182
ARG A 341
ASN A 153
 None
 1.04A 6hisB-4eudA:
undetectable
6hisC-4eudA:
undetectable		 6hisB-4eudA:
9.36
6hisC-4eudA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 8 ASP A 181
ILE A 182
ARG A 341
ASN A 153
 None
 1.04A 6hisC-4eudA:
undetectable
6hisD-4eudA:
undetectable		 6hisC-4eudA:
9.36
6hisD-4eudA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 8 ASP A 181
ILE A 182
ARG A 341
ASN A 153
 None
 1.04A 6hisD-4eudA:
undetectable
6hisE-4eudA:
undetectable		 6hisD-4eudA:
9.36
6hisE-4eudA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		4 / 8 ASN A 153
ASP A 181
ILE A 182
ARG A 341
 None
 1.05A 6hisA-4eudA:
undetectable
6hisE-4eudA:
undetectable		 6hisA-4eudA:
9.36
6hisE-4eudA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 10 ASP A  95
MET A 383
GLY A 271
ALA A 239
ASN A 384
 None
COA  A2598 (-4.1A)
None
None
COA  A2598 (-3.9A)
 1.37A 6hu9L-4eudA:
undetectable
6hu9P-4eudA:
undetectable
6hu9T-4eudA:
undetectable		 6hu9L-4eudA:
20.08
6hu9P-4eudA:
18.35
6hu9T-4eudA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4eud SUCCINYL-COA:ACETATE
COENZYME A
TRANSFERASE
(Acetobacter
aceti) 		5 / 9 ILE A 296
ALA A 312
GLY A 291
LEU A 266
GLY A 307
 None
 1.00A 6nm4B-4eudA:
undetectable		 6nm4B-4eudA:
15.67