SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4euf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 THR A 284
PRO A 286
THR A 168
 None
 0.86A 1dscC-4eufA:
undetectable		 1dscC-4eufA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		4 / 6 PHE A  94
ILE A  92
LYS A  99
ALA A  98
 None
 1.19A 1hk2A-4eufA:
undetectable		 1hk2A-4eufA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		5 / 12 ALA A  61
GLY A  63
ILE A  28
ALA A  98
PHE A  94
 None
 1.12A 1ve3A-4eufA:
5.6		 1ve3A-4eufA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		5 / 12 ALA A  61
GLY A  63
ILE A  28
ALA A  98
PHE A  94
 None
 1.08A 1ve3B-4eufA:
5.9		 1ve3B-4eufA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 ARG A 330
SER A 319
TYR A 318
 None
 0.71A 1x70A-4eufA:
undetectable		 1x70A-4eufA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 SER A 279
GLU A 370
ASP A 363
 NAD  A1001 ( 4.9A)
None
None
 0.90A 2avdB-4eufA:
7.0		 2avdB-4eufA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		4 / 6 ASP A 347
VAL A 346
PRO A 229
THR A 231
 None
 1.09A 2q6oB-4eufA:
undetectable		 2q6oB-4eufA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 THR A 284
PRO A 286
THR A 168
 None
 0.86A 316dC-4eufA:
undetectable		 316dC-4eufA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 MET A 307
GLU A  23
ASP A 378
 None
 0.86A 3a25A-4eufA:
5.6		 3a25A-4eufA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		5 / 12 LEU A 134
ALA A 218
GLY A  39
ILE A 132
SER A 215
 None
 1.33A 3gyqA-4eufA:
undetectable
3gyqB-4eufA:
undetectable		 3gyqA-4eufA:
20.15
3gyqB-4eufA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		4 / 8 GLY A 329
ILE A 317
PHE A 135
PHE A 214
 None
 0.83A 3ko0B-4eufA:
undetectable
3ko0J-4eufA:
undetectable		 3ko0B-4eufA:
13.46
3ko0J-4eufA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		4 / 8 GLY A 329
ILE A 317
PHE A 135
PHE A 214
 None
 0.83A 3ko0K-4eufA:
undetectable
3ko0S-4eufA:
undetectable		 3ko0K-4eufA:
13.46
3ko0S-4eufA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		4 / 7 TYR A  18
LEU A 396
ALA A  78
TYR A  89
 None
 1.07A 3rodD-4eufA:
undetectable		 3rodD-4eufA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 TYR A  74
THR A  76
GLU A 110
 None
 0.83A 4df3B-4eufA:
7.9		 4df3B-4eufA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		3 / 3 THR A 284
PRO A 286
THR A 168
 None
 0.86A 4hivD-4eufA:
undetectable		 4hivD-4eufA:
1.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		4 / 4 VAL A 181
ALA A 184
ILE A 240
THR A 239
 None
 1.20A 5e4dB-4eufA:
undetectable		 5e4dB-4eufA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4euf PUTATIVE REDUCTASE
CA_C0462
(Clostridium
acetobutylicum) 		5 / 12 ILE A 309
PHE A 313
GLY A  63
ILE A  45
LEU A 134
 None
 1.07A 6dwnD-4eufA:
undetectable		 6dwnD-4eufA:
10.74