SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4euk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4euk HISTIDINE KINASE 5
HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		4 / 4 SER B  86
ASP A 828
ASP A 835
ALA A 885
 None
MG  A1001 (-2.5A)
None
None
 1.21A 3uj6A-4eukB:
undetectable		 3uj6A-4eukB:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 4euk HISTIDINE KINASE 5
(Arabidopsis
thaliana) 		5 / 9 ALA A 807
ALA A 839
GLY A 836
ILE A 843
ILE A 814
 None
 1.15A 4eatB-4eukA:
4.5		 4eatB-4eukA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4euk HISTIDINE KINASE 5
(Arabidopsis
thaliana) 		4 / 7 GLU A 847
GLU A 848
GLY A 899
ARG A 844
 None
 1.05A 4fgzA-4eukA:
undetectable		 4fgzA-4eukA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 4euk HISTIDINE KINASE 5
HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		3 / 3 SER B  87
ASP A 785
ASP A 835
 None
MG  A1001 (-2.5A)
None
 0.92A 4mwzA-4eukB:
undetectable		 4mwzA-4eukB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4euk HISTIDINE KINASE 5
(Arabidopsis
thaliana) 		5 / 12 PRO A 879
ARG A 844
ALA A 839
GLY A 836
LEU A 837
 None
 1.22A 4oadA-4eukA:
undetectable		 4oadA-4eukA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4euk HISTIDINE KINASE 5
HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN 1
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		4 / 7 LEU B  30
ILE A 904
MET A 883
MET A 796
 None
 0.98A 5ljcA-4eukB:
undetectable		 5ljcA-4eukB:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4euk HISTIDINE KINASE 5
(Arabidopsis
thaliana) 		4 / 5 ALA A 858
VAL A 860
LYS A 838
ILE A 814
 None
 0.99A 5of1A-4eukA:
undetectable		 5of1A-4eukA:
22.63