SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eun'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 5 MET A  49
ALA A  47
ILE A  46
ASP A  59
 None
 0.79A 1upfA-4eunA:
undetectable		 1upfA-4eunA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 7 MET A  49
ALA A  47
ILE A  46
ASP A  59
 None
 0.87A 1upfB-4eunA:
undetectable		 1upfB-4eunA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 5 MET A  49
ALA A  47
ILE A  46
ASP A  59
 None
 0.69A 1upfC-4eunA:
undetectable		 1upfC-4eunA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 8 MET A 127
PHE A 126
SER A  15
ALA A  37
 None
 0.94A 2o01A-4eunA:
undetectable		 2o01A-4eunA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 8 MET A 127
PHE A 126
SER A  15
ALA A  37
 None
 0.67A 4rkuA-4eunA:
undetectable
4rkuJ-4eunA:
undetectable		 4rkuA-4eunA:
14.89
4rkuJ-4eunA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 7 MET A 127
PHE A 126
SER A  15
ALA A  37
 None
 0.69A 4xk8A-4eunA:
undetectable		 4xk8A-4eunA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4eun THERMORESISTANT
GLUCOKINASE
(Janibacter
sp.
HTCC2649) 		4 / 8 MET A 127
PHE A 126
SER A  15
ALA A  37
 None
 0.67A 4xk8a-4eunA:
undetectable		 4xk8a-4eunA:
14.60