SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4evd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_A_BEZA500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4evd NEUTROPHIL-ACTIVATIN
G PROTEIN
(Helicobacter
pylori) 		5 / 10 ASP A  13
LEU A  17
PHE A  47
HIS A 101
LEU A 132
 None
None
None
CD  A 203 (-3.5A)
None
 1.27A 2q0jA-4evdA:
undetectable		 2q0jA-4evdA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4evd NEUTROPHIL-ACTIVATIN
G PROTEIN
(Helicobacter
pylori) 		5 / 11 ASP A  13
LEU A  17
PHE A  47
HIS A 101
LEU A 132
 None
None
None
CD  A 203 (-3.5A)
None
 1.29A 2q0jB-4evdA:
undetectable		 2q0jB-4evdA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 4evd NEUTROPHIL-ACTIVATIN
G PROTEIN
(Helicobacter
pylori) 		4 / 6 ARG A  57
GLU A  56
GLN A  11
PRO A  65
 None
 1.49A 3gclA-4evdA:
undetectable		 3gclA-4evdA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4evd NEUTROPHIL-ACTIVATIN
G PROTEIN
(Helicobacter
pylori) 		4 / 7 TYR A 124
LEU A  10
ASP A  13
ALA A  14
 None
 1.20A 3rodD-4evdA:
undetectable		 3rodD-4evdA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 4evd NEUTROPHIL-ACTIVATIN
G PROTEIN
(Helicobacter
pylori) 		4 / 7 LYS A  20
PHE A  24
ILE A  95
ASP A  98
 CD  A 215 ( 4.6A)
None
None
None
 0.90A 5yf9B-4evdA:
undetectable		 5yf9B-4evdA:
18.95