SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4evf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
4 / 7 GLU A 124
PHE A  95
MET A 144
ALA A 145
None
1.33A 1linA-4evfA:
undetectable
1linA-4evfA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
5 / 12 PHE A  71
LEU A  66
ILE A  54
ILE A  23
ALA A  24
None
1.02A 2bxqA-4evfA:
undetectable
2bxqA-4evfA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D0K_A_FOLA1161_0
(DIHYDROFOLATE
REDUCTASE)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
6 / 12 ILE A 205
PHE A 178
ILE A 189
LEU A 162
ILE A 201
THR A 216
None
1.43A 2d0kA-4evfA:
undetectable
2d0kA-4evfA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
4 / 4 ILE A 205
PHE A 178
ILE A 201
THR A 216
None
1.16A 3ia4A-4evfA:
undetectable
3ia4A-4evfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
4 / 6 THR A 207
LEU A 162
ASN A 197
GLU A 191
None
1.18A 4nc3A-4evfA:
undetectable
4nc3A-4evfA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
4 / 8 ILE A 276
ARG A 278
GLY A 243
ASN A 240
None
1.00A 5hwaA-4evfA:
undetectable
5hwaA-4evfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
4 / 7 THR A 207
LEU A 162
ASN A 197
GLU A 191
None
1.02A 5tudA-4evfA:
undetectable
5tudA-4evfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis)
5 / 10 LEU A  58
ILE A 287
PHE A  25
ALA A  14
LEU A  11
None
1.21A 5y7pG-4evfA:
undetectable
5y7pG-4evfA:
20.00