SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ew5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4ew5 CIGR PROTEIN
(Salmonella
enterica) 		3 / 3 ALA A 119
VAL A 117
TRP A 133
 None
 0.82A 1tkqA-4ew5A:
undetectable		 1tkqA-4ew5A:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4ew5 CIGR PROTEIN
(Salmonella
enterica) 		4 / 5 GLY A  87
PRO A 118
VAL A 117
ILE A 135
 None
 0.95A 2aoiA-4ew5A:
undetectable		 2aoiA-4ew5A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ew5 CIGR PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 156
ALA A 152
LEU A 125
VAL A 117
ILE A 135
 None
 0.97A 3adxB-4ew5A:
undetectable		 3adxB-4ew5A:
17.07