SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ew9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		3 / 3 ALA A  60
VAL A  82
TRP A  79
 None
CA  A 201 (-4.9A)
None
 0.86A 1c4dC-4ew9A:
undetectable
1c4dD-4ew9A:
undetectable		 1c4dC-4ew9A:
11.76
1c4dD-4ew9A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 12 LEU A  53
LEU A  47
VAL A  14
VAL A  56
LEU A   6
 None
None
None
None
MPD  A 207 ( 3.8A)
 1.35A 1db1A-4ew9A:
undetectable		 1db1A-4ew9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.30A 3j6gB-4ew9A:
undetectable		 3j6gB-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gD-4ew9A:
undetectable		 3j6gD-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gF-4ew9A:
undetectable		 3j6gF-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gH-4ew9A:
undetectable		 3j6gH-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gJ-4ew9A:
undetectable		 3j6gJ-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gL-4ew9A:
undetectable		 3j6gL-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gN-4ew9A:
undetectable		 3j6gN-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.29A 3j6gP-4ew9A:
undetectable		 3j6gP-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 10 VAL A  82
ASP A  81
LEU A 131
PHE A 123
THR A 150
 CA  A 201 (-4.9A)
CA  A 201 (-3.0A)
None
None
None
 1.30A 3j6gR-4ew9A:
undetectable		 3j6gR-4ew9A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		3 / 3 GLU A  39
ASP A  64
ASP A 107
 CA  A 204 (-2.2A)
CA  A 202 (-2.3A)
UNG  A 209 ( 3.3A)
 0.61A 3jb2A-4ew9A:
undetectable		 3jb2A-4ew9A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		4 / 6 THR A   0
ASN A   1
GLY A  22
ASP A  21
 None
MPD  A 207 (-4.7A)
None
None
 0.81A 3w9tE-4ew9A:
undetectable		 3w9tE-4ew9A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		4 / 6 THR A   0
ASN A   1
GLY A  22
ASP A  21
 None
MPD  A 207 (-4.7A)
None
None
 0.82A 3w9tF-4ew9A:
undetectable		 3w9tF-4ew9A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		3 / 3 ASP A 162
ASN A 113
GLN A 111
 None
DGU  A 210 (-3.4A)
UNG  A 209 ( 3.4A)
 0.69A 5k7uA-4ew9A:
undetectable		 5k7uA-4ew9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 4ew9 PECTATE LYASE
(Caldicellulosiru
ptor
bescii) 		5 / 12 LEU A   6
ILE A  25
GLY A   4
ILE A   8
ILE A  27
 MPD  A 207 ( 3.8A)
MPD  A 207 ( 4.8A)
None
MPD  A 206 (-4.4A)
None
 0.94A 6emuA-4ew9A:
undetectable		 6emuA-4ew9A:
22.87