SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ewc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		6 / 12 GLY A 290
GLY A 305
THR A 379
ALA A 446
ALA A 288
PHE A 447
 None
 1.44A 2gluB-4ewcA:
undetectable		 2gluB-4ewcA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 12 GLN A 266
GLY A 271
GLY A 290
LEU A 262
ALA A 104
 None
 1.07A 3kkzB-4ewcA:
undetectable		 3kkzB-4ewcA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 10 ALA A 150
LEU A 151
PHE A 155
ARG A 230
ALA A 172
 None
 1.05A 4j14A-4ewcA:
undetectable		 4j14A-4ewcA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 12 THR A 286
THR A 285
ALA A 288
SER A 449
ALA A 446
 None
 1.10A 5lf7V-4ewcA:
undetectable
5lf7b-4ewcA:
undetectable		 5lf7V-4ewcA:
18.57
5lf7b-4ewcA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 12 THR A 286
THR A 285
ALA A 288
SER A 449
ALA A 446
 None
 1.10A 5lf7H-4ewcA:
undetectable
5lf7N-4ewcA:
undetectable		 5lf7H-4ewcA:
18.57
5lf7N-4ewcA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 12 LEU A 390
ILE A 394
GLY A 170
LEU A 177
ILE A 257
 None
 0.92A 5m24A-4ewcA:
undetectable		 5m24A-4ewcA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 12 ALA A 172
VAL A 423
ALA A 434
LEU A 487
LEU A 421
 None
 1.03A 5xxiA-4ewcA:
undetectable		 5xxiA-4ewcA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		4 / 8 LEU A 151
ASN A 204
VAL A 217
LEU A 222
 None
 0.72A 6cb4A-4ewcA:
undetectable		 6cb4A-4ewcA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		5 / 12 ILE A 387
PHE A 148
LEU A 177
PHE A 143
ILE A 415
 None
 1.16A 6dwnB-4ewcA:
undetectable		 6dwnB-4ewcA:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 4ewc PUTATIVE
NUCLEOPROTEIN
(Salmon
isavirus) 		3 / 3 ARG A 491
GLY A 567
GLU A 568
 None
 0.62A 6fgdA-4ewcA:
undetectable		 6fgdA-4ewcA:
23.62