SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4exj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 7 THR A  64
VAL A  56
ASP A  57
ILE A  63
 None
 0.95A 1p7rA-4exjA:
undetectable		 1p7rA-4exjA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		5 / 12 VAL A 162
THR A 160
ASP A  78
ASN A  68
ILE A  69
 None
 1.03A 3a3bA-4exjA:
undetectable		 3a3bA-4exjA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		5 / 12 ALA A 165
LEU A 167
GLY A  10
PRO A  15
LEU A   4
 None
None
SO4  A 302 (-3.7A)
None
None
 1.05A 3tm4A-4exjA:
undetectable		 3tm4A-4exjA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		5 / 12 ALA A 165
LEU A 167
GLY A  10
PRO A  15
LEU A   4
 None
None
SO4  A 302 (-3.7A)
None
None
 1.06A 3tm4B-4exjA:
undetectable		 3tm4B-4exjA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 8 ASN A 205
MET A  30
LEU A  16
ILE A 201
 None
 0.96A 4ok1A-4exjA:
undetectable		 4ok1A-4exjA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		5 / 12 ILE A  69
VAL A  17
VAL A 168
PHE A  31
TYR A  43
 None
 1.19A 5igiA-4exjA:
undetectable		 5igiA-4exjA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 4exj UNCHARACTERIZED
PROTEIN
(Lodderomyces
elongisporus) 		4 / 6 GLU A 216
HIS A  32
ALA A 214
GLN A 221
 None
 1.29A 6f6jC-4exjA:
undetectable
6f6jD-4exjA:
undetectable		 6f6jC-4exjA:
19.79
6f6jD-4exjA:
19.79