SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4exn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4exn INTERLEUKIN-34
(Mus
musculus) 		4 / 5 LEU A  37
TRP A  94
LEU A 126
MET A 134
 None
 1.05A 2oaxA-4exnA:
undetectable		 2oaxA-4exnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_2
(MINERALOCORTICOID
RECEPTOR)		 4exn INTERLEUKIN-34
(Mus
musculus) 		4 / 4 LEU A  37
TRP A  94
LEU A 126
MET A 134
 None
 1.38A 2oaxE-4exnA:
0.0		 2oaxE-4exnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 165
TRP A 116
TYR A  53
 None
 0.88A 3aicA-4exnA:
undetectable		 3aicA-4exnA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 165
TRP A 116
TYR A  53
 None
 0.92A 3aicB-4exnA:
undetectable		 3aicB-4exnA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 165
TRP A 116
TYR A  53
 None
 0.92A 3aicE-4exnA:
undetectable		 3aicE-4exnA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 165
TRP A 116
TYR A  53
 None
 0.89A 3aicF-4exnA:
undetectable		 3aicF-4exnA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 165
TRP A 116
TYR A  53
 None
 0.93A 3aicG-4exnA:
undetectable		 3aicG-4exnA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 165
TRP A 116
TYR A  53
 None
 0.91A 3aicH-4exnA:
undetectable		 3aicH-4exnA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 4exn INTERLEUKIN-34
(Mus
musculus) 		3 / 3 LEU A 133
VAL A  85
ARG A  88
 None
 0.87A 3b0wB-4exnA:
undetectable		 3b0wB-4exnA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4exn INTERLEUKIN-34
(Mus
musculus) 		4 / 4 LEU A 156
LEU A 154
GLY A 153
GLU A  69
 None
None
None
NAG  A 202 ( 2.9A)
 1.22A 5hhjA-4exnA:
undetectable		 5hhjA-4exnA:
22.54