SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eyc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		4 / 5 LYS A  75
PRO A  76
SER A  78
LEU A 114
 None
 1.06A 3ijxH-4eycA:
undetectable		 3ijxH-4eycA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		4 / 5 LYS A  75
PRO A  76
SER A  78
LEU A 114
 None
 1.18A 3iluH-4eycA:
undetectable		 3iluH-4eycA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		5 / 12 ILE A 123
GLY A 110
PHE A 121
VAL A  77
PRO A  74
 None
 1.06A 3jb3A-4eycA:
undetectable		 3jb3A-4eycA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		5 / 12 ASN A  47
GLY A  45
VAL A  39
LEU A  58
THR A  84
 None
 1.16A 3mnoA-4eycA:
undetectable		 3mnoA-4eycA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		5 / 12 ASN A  47
GLY A  45
VAL A  39
LEU A  58
THR A  84
 None
 1.16A 3mnpA-4eycA:
undetectable		 3mnpA-4eycA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		5 / 12 THR A  90
PRO A  87
ASN A  47
ILE A  46
VAL A  81
 None
 1.27A 4eb6B-4eycA:
undetectable
4eb6C-4eycA:
undetectable		 4eb6B-4eycA:
14.77
4eb6C-4eycA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		5 / 12 HIS A  -1
SER A  -2
SER A 120
GLY A 119
ALA A 117
 None
 1.29A 5l5zV-4eycA:
undetectable
5l5zb-4eycA:
undetectable		 5l5zV-4eycA:
15.32
5l5zb-4eycA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4eyc CATHELICIDIN
ANTIMICROBIAL
PEPTIDE
(Homo
sapiens) 		5 / 12 HIS A  -1
SER A  -2
SER A 120
GLY A 119
ALA A 117
 None
 1.29A 5l5zH-4eycA:
undetectable
5l5zN-4eycA:
undetectable		 5l5zH-4eycA:
15.32
5l5zN-4eycA:
18.37