SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eyv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 6 PHE A  36
ILE A  78
LYS A  41
ALA A  40
 None
 0.98A 1hk2A-4eyvA:
undetectable		 1hk2A-4eyvA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		3 / 3 TYR A  48
GLY A  50
PHE A  67
 None
 0.71A 2m2pB-4eyvA:
undetectable		 2m2pB-4eyvA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 6 PHE A  22
PHE A  36
GLY A  64
GLY A  65
 None
None
NA  A 203 ( 3.7A)
NA  A 203 (-4.2A)
 0.90A 2qr2A-4eyvA:
undetectable
2qr2B-4eyvA:
undetectable		 2qr2A-4eyvA:
22.88
2qr2B-4eyvA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 5 GLY A  64
GLY A  65
PHE A  22
PHE A  36
 NA  A 203 ( 3.7A)
NA  A 203 (-4.2A)
None
None
 0.83A 2qr2A-4eyvA:
undetectable
2qr2B-4eyvA:
undetectable		 2qr2A-4eyvA:
22.88
2qr2B-4eyvA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 6 PHE A  22
PHE A  36
GLY A  64
GLY A  65
 None
None
NA  A 203 ( 3.7A)
NA  A 203 (-4.2A)
 0.78A 2qx6A-4eyvA:
undetectable
2qx6B-4eyvA:
undetectable		 2qx6A-4eyvA:
22.88
2qx6B-4eyvA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 6 THR A 119
SER A  99
LEU A  97
THR A 115
 None
 0.85A 3deuB-4eyvA:
undetectable		 3deuB-4eyvA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 4 ASN A  16
VAL A 138
THR A 159
ILE A 158
 None
 0.92A 4retA-4eyvA:
undetectable		 4retA-4eyvA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 4 ASN A  16
VAL A 138
THR A 159
ILE A 158
 None
 0.92A 4retC-4eyvA:
undetectable		 4retC-4eyvA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 6 ILE A  57
PRO A  58
ILE A  12
VAL A 156
 None
 0.94A 4zj8A-4eyvA:
undetectable		 4zj8A-4eyvA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		4 / 6 ILE A 114
LEU A  62
PHE A  53
ARG A  19
 None
 1.04A 5b1aN-4eyvA:
undetectable
5b1aW-4eyvA:
undetectable		 5b1aN-4eyvA:
17.98
5b1aW-4eyvA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 4eyv PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Serendipita
indica) 		5 / 12 GLY A 109
ILE A  78
ASN A 102
PHE A  36
LEU A  98
 None
 1.00A 5fa8A-4eyvA:
undetectable		 5fa8A-4eyvA:
23.76