SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4eyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4eyy ICMQ
ICMR
(Legionella
pneumophila) 		4 / 6 ARG Q  43
ILE R  41
VAL R  79
LEU R  75
 None
 1.11A 4em2A-4eyyQ:
undetectable		 4em2A-4eyyQ:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4eyy ICMQ
(Legionella
pneumophila) 		5 / 7 GLY Q  86
GLN Q 126
SER Q  83
ASN Q 127
HIS Q 175
 None
 1.43A 4ws0A-4eyyQ:
undetectable		 4ws0A-4eyyQ:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4eyy ICMQ
(Legionella
pneumophila) 		3 / 3 ALA Q 110
TYR Q 109
PRO Q 149
 None
 0.69A 4zdyA-4eyyQ:
undetectable		 4zdyA-4eyyQ:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4eyy ICMQ
ICMR
(Legionella
pneumophila;
Legionella
pneumophila) 		5 / 9 GLY Q  24
ILE Q  35
GLY Q  36
LEU Q  39
ILE R  42
 None
 0.81A 5vkqC-4eyyQ:
3.5
5vkqD-4eyyQ:
3.6		 5vkqC-4eyyQ:
7.64
5vkqD-4eyyQ:
7.64