SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ezb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		3 / 4 LYS A 180
ALA A 257
MET A 237
 None
 1.03A 1hk3A-4ezbA:
2.3		 1hk3A-4ezbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 ILE A  62
ALA A   5
VAL A  68
VAL A  72
ALA A  81
 None
 1.21A 1n4hA-4ezbA:
undetectable		 1n4hA-4ezbA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		4 / 5 GLY A 141
GLU A 121
GLY A 162
PRO A 165
 None
 0.95A 3onnA-4ezbA:
3.9		 3onnA-4ezbA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		3 / 3 GLY A   8
ASP A  32
ASP A  37
 None
 0.46A 3ou7C-4ezbA:
3.5		 3ou7C-4ezbA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.15A 4mm5A-4ezbA:
undetectable		 4mm5A-4ezbA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 11 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.17A 4mm9A-4ezbA:
undetectable		 4mm9A-4ezbA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.18A 4mmbA-4ezbA:
1.3		 4mmbA-4ezbA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 PRO A  55
VAL A  53
ALA A  29
GLY A  10
PHE A   9
 None
 1.31A 4mmbA-4ezbA:
1.3		 4mmbA-4ezbA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.18A 4mmdB-4ezbA:
undetectable		 4mmdB-4ezbA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.19A 4mmeA-4ezbA:
undetectable		 4mmeA-4ezbA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.20A 4mmeB-4ezbA:
undetectable		 4mmeB-4ezbA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.15A 4mmfA-4ezbA:
undetectable		 4mmfA-4ezbA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 9 ASP A  96
ALA A  13
GLY A  74
SER A  70
GLY A   8
 None
 1.17A 4mmfB-4ezbA:
undetectable		 4mmfB-4ezbA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 LEU A  56
THR A   3
ALA A   5
ILE A   7
ILE A  62
 None
 1.06A 4o2bB-4ezbA:
undetectable		 4o2bB-4ezbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 LEU A 190
LEU A 290
VAL A 285
THR A 226
ILE A 261
 None
 1.25A 4okbA-4ezbA:
undetectable		 4okbA-4ezbA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		4 / 6 LEU A  28
MET A 156
LEU A  69
ILE A  62
 None
 1.11A 4okxA-4ezbA:
undetectable		 4okxA-4ezbA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		5 / 12 LEU A  56
THR A   3
ALA A   5
ILE A   7
ILE A  62
 None
 1.03A 5mioB-4ezbA:
4.2		 5mioB-4ezbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4ezb UNCHARACTERIZED
CONSERVED PROTEIN
(Sinorhizobium
meliloti) 		4 / 4 GLY A  21
ALA A  25
MET A 156
THR A   2
 None
 1.36A 5n0sB-4ezbA:
undetectable		 5n0sB-4ezbA:
22.27