SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ezg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		4 / 8 SER A 150
SER A 172
ASN A 193
ASP A 146
 None
 1.27A 1hwiB-4ezgA:
undetectable		 1hwiB-4ezgA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		4 / 8 ASP A 146
ILE A 177
GLY A 175
GLY A 125
 None
 0.79A 1me7A-4ezgA:
undetectable		 1me7A-4ezgA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		4 / 4 GLY A 125
SER A 150
ILE A 133
HIS A 152
 None
 1.27A 1yajJ-4ezgA:
undetectable		 1yajJ-4ezgA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		4 / 6 ILE A 104
PRO A 134
LEU A 121
ILE A 112
 None
 0.99A 2q83B-4ezgA:
undetectable		 2q83B-4ezgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		5 / 11 ALA A 106
LEU A 121
LEU A  99
LEU A  87
LEU A 115
 None
 1.06A 2xn5A-4ezgA:
undetectable		 2xn5A-4ezgA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		6 / 12 ASP A  98
LEU A 121
ILE A 147
ASP A 170
LEU A 142
LEU A 163
 None
 1.40A 3cjtC-4ezgA:
undetectable		 3cjtC-4ezgA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		5 / 12 TYR A  76
ALA A  80
LEU A  79
VAL A  84
LEU A  54
 None
 1.00A 3ozuA-4ezgA:
undetectable		 3ozuA-4ezgA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		4 / 7 ASP A 170
SER A 172
HIS A 149
SER A 148
 None
 1.25A 4k7gB-4ezgA:
undetectable		 4k7gB-4ezgA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4ezg PUTATIVE
UNCHARACTERIZED
PROTEIN
(Listeria
monocytogenes) 		4 / 5 THR A 185
LEU A 171
VAL A 199
LEU A 214
 None
 0.92A 6bqgA-4ezgA:
undetectable		 6bqgA-4ezgA:
15.74