SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f06'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		3 / 3 ALA A  51
VAL A  53
TRP A  52
 None
 0.86A 1bdwA-4f06A:
undetectable
1bdwB-4f06A:
undetectable		 1bdwA-4f06A:
3.33
1bdwB-4f06A:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ0_A_ACRA801_1
(ALPHA-GLUCOSIDASE
(ALPHA-GLUCOSIDASE
SUSB))		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		5 / 12 ASN A  44
SER A 305
GLU A 376
PHE A 287
GLU A 256
 None
 1.29A 2zq0A-4f06A:
2.3		 2zq0A-4f06A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 5 GLN A 145
ASP A 385
HIS A 355
ARG A 138
 None
 1.11A 3r4xA-4f06A:
undetectable		 3r4xA-4f06A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 5 GLN A 145
ASP A 385
HIS A 355
ARG A 138
 None
 1.15A 3r55A-4f06A:
undetectable		 3r55A-4f06A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		3 / 3 GLU A  72
GLY A  32
SER A  80
 None
 0.61A 4b53B-4f06A:
undetectable		 4b53B-4f06A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		3 / 3 GLN A 145
HIS A 355
ARG A 138
 None
 1.07A 4qyqB-4f06A:
undetectable		 4qyqB-4f06A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 6 GLN A 145
ASP A 385
HIS A 355
ARG A 138
 None
 1.22A 4qyqC-4f06A:
undetectable		 4qyqC-4f06A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 6 PHE A 101
SER A  80
PRO A 103
LEU A  99
 None
None
SO4  A 404 (-3.5A)
None
 1.22A 5dzka-4f06A:
undetectable
5dzko-4f06A:
undetectable		 5dzka-4f06A:
21.52
5dzko-4f06A:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 6 GLN A 145
ASP A 385
HIS A 355
ARG A 138
 None
 1.22A 5hpwC-4f06A:
undetectable		 5hpwC-4f06A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		3 / 3 GLN A 145
THR A 142
ASP A 385
 None
 0.82A 5k9dA-4f06A:
undetectable		 5k9dA-4f06A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LI8_A_KKKA502_1
(PUTATIVE CYTOCHROME
P450 126)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		5 / 12 THR A 255
PRO A 257
PHE A  41
ALA A 289
SER A 305
 None
 1.35A 5li8A-4f06A:
0.0		 5li8A-4f06A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 6 SER A 140
ASP A 385
GLN A 358
THR A 102
 None
None
None
PHB  A 401 ( 3.7A)
 1.47A 6djzA-4f06A:
undetectable		 6djzA-4f06A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 4f06 EXTRACELLULAR
LIGAND-BINDING
RECEPTOR
(Rhodopseudomonas
palustris) 		4 / 8 VAL A 306
ASN A 359
TYR A 361
GLU A 346
 None
 1.20A 6gneB-4f06A:
2.1		 6gneB-4f06A:
22.16