SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		3 / 3 TRP A  20
ALA A  23
VAL A  21
 None
 0.91A 1bdwA-4f0bA:
undetectable
1bdwB-4f0bA:
undetectable		 1bdwA-4f0bA:
7.78
1bdwB-4f0bA:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		6 / 12 LEU A  29
LEU A  91
LEU A  88
ILE A 181
ILE A  24
ALA A  23
 None
 1.17A 2bxqA-4f0bA:
undetectable		 2bxqA-4f0bA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		4 / 7 GLU A 211
GLU A 208
GLY A 185
ARG A 188
 None
 1.02A 4fgzA-4f0bA:
undetectable		 4fgzA-4f0bA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A 172
VAL A 216
ASP A 180
ILE A 210
GLU A 211
 None
 1.38A 4i41A-4f0bA:
undetectable		 4i41A-4f0bA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		4 / 6 ASP A 198
ASN A 202
TYR A 159
ASP A 196
 None
 1.12A 4mdaA-4f0bA:
undetectable		 4mdaA-4f0bA:
21.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		4 / 4 LEU A  89
LEU A 119
SER A 102
ALA A 179
 None
 1.08A 5uunA-4f0bA:
25.4		 5uunA-4f0bA:
30.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4f0b THIOL TRANSFERASE
(Phanerochaete
chrysosporium) 		4 / 6 VAL A   9
LEU A  26
LEU A  29
LEU A  88
 None
 1.04A 6f6sA-4f0bA:
undetectable
6f6sB-4f0bA:
undetectable		 6f6sA-4f0bA:
18.82
6f6sB-4f0bA:
14.49