SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 11 TYR A 293
THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.21A 1akdA-4f0qA:
undetectable		 1akdA-4f0qA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 8 LEU A 156
ALA A 182
VAL A 210
VAL A 112
 None
 0.57A 1epbB-4f0qA:
undetectable		 1epbB-4f0qA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 LEU A 206
LEU A 158
LEU A 156
ILE A  68
GLY A  67
 None
 1.14A 1g50B-4f0qA:
undetectable		 1g50B-4f0qA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 11 LEU A 206
LEU A 158
LEU A 156
ILE A  68
GLY A  67
 None
 1.14A 1g50C-4f0qA:
undetectable		 1g50C-4f0qA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 10 TYR A 293
THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.21A 1o76A-4f0qA:
undetectable		 1o76A-4f0qA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 0.97A 1t85A-4f0qA:
undetectable		 1t85A-4f0qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 1.04A 1t85A-4f0qA:
undetectable		 1t85A-4f0qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 0.98A 1t87A-4f0qA:
undetectable		 1t87A-4f0qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 0.99A 1t87A-4f0qA:
undetectable		 1t87A-4f0qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.02A 1yrcA-4f0qA:
undetectable		 1yrcA-4f0qA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.01A 1yrdA-4f0qA:
undetectable		 1yrdA-4f0qA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 0.97A 1yrdA-4f0qA:
undetectable		 1yrdA-4f0qA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 11 TYR A 293
THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.22A 2a1nA-4f0qA:
undetectable		 2a1nA-4f0qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 SER A  80
ARG A 140
LEU A 141
GLU A 149
 None
 1.11A 2cdqB-4f0qA:
undetectable		 2cdqB-4f0qA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.00A 2feuA-4f0qA:
undetectable		 2feuA-4f0qA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.00A 2feuB-4f0qA:
undetectable		 2feuB-4f0qA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 0.97A 2zuhA-4f0qA:
undetectable		 2zuhA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 0.91A 2zuhA-4f0qA:
undetectable		 2zuhA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.01A 2zuiA-4f0qA:
undetectable		 2zuiA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 0.99A 2zuiA-4f0qA:
undetectable		 2zuiA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.02A 2zwtA-4f0qA:
undetectable		 2zwtA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 1.00A 2zwtA-4f0qA:
undetectable		 2zwtA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.03A 2zwuA-4f0qA:
undetectable		 2zwuA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 1.00A 2zwuA-4f0qA:
undetectable		 2zwuA-4f0qA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 9 TYR A 293
THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.23A 3cppA-4f0qA:
undetectable		 3cppA-4f0qA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		6 / 10 TYR A 114
ILE A  85
ILE A  68
GLY A 116
PRO A 126
LEU A 208
 None
 1.48A 3elzB-4f0qA:
undetectable		 3elzB-4f0qA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.00A 3fwfA-4f0qA:
undetectable		 3fwfA-4f0qA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.02A 3fwfB-4f0qA:
undetectable		 3fwfB-4f0qA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.04A 3fwiA-4f0qA:
undetectable		 3fwiA-4f0qA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 0.98A 3fwiA-4f0qA:
undetectable		 3fwiA-4f0qA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.01A 3fwjA-4f0qA:
undetectable		 3fwjA-4f0qA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.03A 3l63A-4f0qA:
undetectable		 3l63A-4f0qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 5 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.02A 3w9tA-4f0qA:
undetectable		 3w9tA-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.02A 3w9tB-4f0qA:
undetectable		 3w9tB-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 5 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.01A 3w9tC-4f0qA:
undetectable		 3w9tC-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 5 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.03A 3w9tD-4f0qA:
undetectable		 3w9tD-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.01A 3w9tE-4f0qA:
undetectable		 3w9tE-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 6 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.04A 3w9tF-4f0qA:
undetectable		 3w9tF-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 5 ASP A  78
GLU A 236
GLY A 235
GLU A 148
 None
 1.02A 3w9tG-4f0qA:
undetectable		 3w9tG-4f0qA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.00A 3wrhA-4f0qA:
undetectable		 3wrhA-4f0qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.02A 3wrjA-4f0qA:
undetectable		 3wrjA-4f0qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.01A 3wrlA-4f0qA:
undetectable		 3wrlA-4f0qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.02A 3wrmA-4f0qA:
undetectable		 3wrmA-4f0qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.00A 3wrmF-4f0qA:
undetectable		 3wrmF-4f0qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 THR A 437
LEU A 302
ALA A 304
SER A 305
ARG A 306
 None
 1.37A 4ejwA-4f0qA:
undetectable		 4ejwA-4f0qA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 9 TYR A 293
THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 1.19A 4ek1B-4f0qA:
undetectable		 4ek1B-4f0qA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 PHE A 335
GLU A 451
ARG A 376
LEU A 377
VAL A 373
 None
 1.31A 4k39A-4f0qA:
undetectable		 4k39A-4f0qA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		3 / 3 LYS A 119
PRO A 120
SER A 121
 None
 0.40A 4k50I-4f0qA:
undetectable		 4k50I-4f0qA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 0.99A 4l4gA-4f0qA:
undetectable		 4l4gA-4f0qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 TYR A 293
THR A 437
LEU A 433
VAL A 418
 None
 1.03A 4l4gA-4f0qA:
undetectable		 4l4gA-4f0qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 ALA A 284
GLN A 287
LEU A 289
GLY A 412
ALA A 416
 None
 1.22A 4pclA-4f0qA:
undetectable		 4pclA-4f0qA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 PHE A 157
ALA A 182
HIS A 142
PRO A 155
 None
 1.01A 5dzkD-4f0qA:
undetectable
5dzkR-4f0qA:
undetectable		 5dzkD-4f0qA:
18.64
5dzkR-4f0qA:
0.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 8 PHE A 157
ALA A 182
HIS A 142
PRO A 155
 None
 1.00A 5dzkd-4f0qA:
undetectable
5dzkr-4f0qA:
undetectable		 5dzkd-4f0qA:
18.64
5dzkr-4f0qA:
0.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 8 PHE A 157
ALA A 182
HIS A 142
PRO A 155
 None
 1.01A 5dzkF-4f0qA:
undetectable
5dzkT-4f0qA:
undetectable		 5dzkF-4f0qA:
18.64
5dzkT-4f0qA:
0.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 4 ILE A 183
ILE A 256
ARG A 253
LEU A 208
 None
 0.86A 5dzkh-4f0qA:
undetectable
5dzkn-4f0qA:
undetectable
5dzkv-4f0qA:
undetectable		 5dzkh-4f0qA:
17.42
5dzkn-4f0qA:
17.42
5dzkv-4f0qA:
0.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 ALA A 356
GLY A 354
ARG A 326
GLY A 332
 MG  A 501 (-4.5A)
None
None
None
 0.87A 5e26A-4f0qA:
undetectable
5e26B-4f0qA:
undetectable		 5e26A-4f0qA:
23.62
5e26B-4f0qA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 GLY A 354
ARG A 326
GLY A 332
ALA A 356
 None
None
None
MG  A 501 (-4.5A)
 0.87A 5e26C-4f0qA:
undetectable
5e26D-4f0qA:
undetectable		 5e26C-4f0qA:
23.62
5e26D-4f0qA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		3 / 3 VAL A 365
ARG A 419
PRO A 276
 None
 0.79A 5koxA-4f0qA:
undetectable		 5koxA-4f0qA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		3 / 3 THR A  98
PRO A 195
ASP A 194
 None
 0.93A 5l8dB-4f0qA:
undetectable		 5l8dB-4f0qA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		3 / 3 THR A  98
PRO A 195
ASP A 194
 None
 0.93A 5mwuB-4f0qA:
undetectable		 5mwuB-4f0qA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 9 GLY A 131
LEU A 135
ILE A  87
GLY A  67
ILE A 224
 None
 0.98A 5vkqC-4f0qA:
undetectable
5vkqD-4f0qA:
undetectable		 5vkqC-4f0qA:
14.84
5vkqD-4f0qA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		4 / 7 THR A 437
LEU A 433
VAL A 418
VAL A 386
 None
 0.95A 5wk9A-4f0qA:
undetectable		 5wk9A-4f0qA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 GLY A 116
PHE A 115
ASN A 203
ALA A  66
ASP A 106
 None
 1.18A 5x66A-4f0qA:
undetectable
5x66B-4f0qA:
undetectable		 5x66A-4f0qA:
19.73
5x66B-4f0qA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 MET A 421
ALA A 308
PHE A 115
THR A 413
LEU A 414
 None
 1.07A 6djzC-4f0qA:
undetectable		 6djzC-4f0qA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 THR A 388
VAL A 386
ASP A 294
PHE A 300
PHE A 335
 None
 1.40A 6iblA-4f0qA:
undetectable		 6iblA-4f0qA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4f0q RESTRICTION
ENDONUCLEASE
(Mycobacterium
sp.
JLS) 		5 / 12 THR A 388
VAL A 386
ASP A 294
PHE A 300
PHE A 335
 None
 1.39A 6iblB-4f0qA:
undetectable		 6iblB-4f0qA:
21.29