SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f2e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 4f2e CUPA
(Streptococcus
pneumoniae) 		4 / 5 VAL A  65
PHE A  83
ARG A  42
ARG A  68
 None
 1.45A 3bjwE-4f2eA:
undetectable		 3bjwE-4f2eA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4f2e CUPA
(Streptococcus
pneumoniae) 		3 / 3 GLY A  47
ASP A  70
SER A  72
 None
 0.71A 3brfA-4f2eA:
undetectable		 3brfA-4f2eA:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 4f2e CUPA
(Streptococcus
pneumoniae) 		5 / 11 ILE A  78
ILE A  54
PHE A 109
ILE A  99
VAL A  97
 None
 0.88A 3kw4A-4f2eA:
undetectable		 3kw4A-4f2eA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4f2e CUPA
(Streptococcus
pneumoniae) 		4 / 5 VAL A  65
PHE A  80
ILE A  99
PHE A  83
 None
 1.02A 3owxB-4f2eA:
undetectable		 3owxB-4f2eA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f2e CUPA
(Streptococcus
pneumoniae) 		4 / 4 GLU A  52
PRO A  51
ILE A  54
LEU A  53
 None
 1.07A 5m45A-4f2eA:
undetectable		 5m45A-4f2eA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f2e CUPA
(Streptococcus
pneumoniae) 		4 / 4 GLU A  52
PRO A  51
ILE A  54
LEU A  53
 None
 1.10A 5m45D-4f2eA:
undetectable		 5m45D-4f2eA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f2e CUPA
(Streptococcus
pneumoniae) 		4 / 4 GLU A  52
PRO A  51
ILE A  54
LEU A  53
 None
 1.06A 5m45G-4f2eA:
undetectable		 5m45G-4f2eA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f2e CUPA
(Streptococcus
pneumoniae) 		4 / 4 GLU A  52
PRO A  51
ILE A  54
LEU A  53
 None
 1.09A 5m45J-4f2eA:
undetectable		 5m45J-4f2eA:
8.64