SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4f2m SPIKE PROTEIN
(Alphacoronavirus
1) 		5 / 12 VAL E 560
THR E 540
LEU E 614
ILE E 517
THR E 513
 None
 1.21A 3qfxB-4f2mE:
undetectable		 3qfxB-4f2mE:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 4f2m SPIKE PROTEIN
(Alphacoronavirus
1) 		5 / 12 PHE E 610
ILE E 553
SER E 559
VAL E 652
PHE E 558
 None
 1.37A 6ap6B-4f2mE:
undetectable		 6ap6B-4f2mE:
20.51