SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f3p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		5 / 11 LEU A 169
ILE A 135
PRO A 153
ASN A 131
ARG A 157
 None
 1.05A 2ft9A-4f3pA:
undetectable		 2ft9A-4f3pA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		4 / 7 ASP A 110
TYR A 109
TYR A 108
PRO A 107
 None
 1.36A 2q6kA-4f3pA:
undetectable		 2q6kA-4f3pA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 ILE A 162
ASP A 180
LEU A 113
ALA A 114
ILE A 144
 None
 1.05A 3dauA-4f3pA:
undetectable		 3dauA-4f3pA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 PHE A 212
LEU A 226
SER A 105
ILE A  58
LEU A  54
 None
 1.14A 3ko0G-4f3pA:
undetectable
3ko0H-4f3pA:
undetectable
3ko0I-4f3pA:
undetectable
3ko0J-4f3pA:
undetectable		 3ko0G-4f3pA:
18.83
3ko0H-4f3pA:
18.83
3ko0I-4f3pA:
18.83
3ko0J-4f3pA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		4 / 8 ALA A 114
LEU A 185
ASP A 180
ASP A 206
 None
 1.00A 3qj7A-4f3pA:
undetectable
3qj7D-4f3pA:
undetectable		 3qj7A-4f3pA:
22.95
3qj7D-4f3pA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		6 / 12 LEU A 113
ALA A 114
LEU A 185
SER A 111
GLY A 192
LEU A 169
 None
 1.43A 4dm8B-4f3pA:
undetectable		 4dm8B-4f3pA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JIN_A_SAMA1205_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT2)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 GLY A 209
TYR A 235
PHE A 243
PHE A  39
GLN A 300
 None
 1.47A 5jinA-4f3pA:
undetectable		 5jinA-4f3pA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4f3p GLUTAMINE-BINDING
PERIPLASMIC PROTEIN
(Burkholderia
pseudomallei) 		5 / 12 TRP A  64
ILE A  68
GLY A 211
LEU A 218
ILE A  58
 None
 1.11A 5m24A-4f3pA:
undetectable		 5m24A-4f3pA:
22.84