SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 4f3r PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Coxiella
burnetii) 		6 / 11 ALA A  25
ILE A 115
GLY A  88
PRO A   8
VAL A  34
ILE A  32
 None
 1.48A 2fxeB-4f3rA:
undetectable		 2fxeB-4f3rA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 4f3r PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Coxiella
burnetii) 		5 / 12 ILE A  85
LEU A  72
ALA A  77
PRO A   8
LEU A  69
 None
 1.06A 3vrmA-4f3rA:
undetectable		 3vrmA-4f3rA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4f3r PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Coxiella
burnetii) 		4 / 5 GLY A   9
THR A  10
HIS A  18
SER A 127
 None
 0.23A 6jmjA-4f3rA:
23.2		 6jmjA-4f3rA:
48.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4f3r PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Coxiella
burnetii) 		6 / 7 GLY A   9
THR A  10
PHE A  11
HIS A  18
ARG A  90
SER A 127
 None
 0.41A 6jnhA-4f3rA:
23.2		 6jnhA-4f3rA:
48.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4f3r PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Coxiella
burnetii) 		5 / 6 GLY A   9
THR A  10
HIS A  18
ARG A  90
SER A 127
 None
 0.40A 6jogA-4f3rA:
23.2		 6jogA-4f3rA:
48.48