SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 ALA A 127
ASP A 196
SER A  19
PRO A  21
ILE A  76
 DAL  A 302 (-3.5A)
None
None
None
DAL  A 302 (-4.9A)
 1.19A 3clbB-4f3sA:
undetectable		 3clbB-4f3sA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 ILE A  78
ASP A 196
THR A  79
ILE A  86
ILE A  76
 None
None
None
None
DAL  A 302 (-4.9A)
 0.99A 3kpdC-4f3sA:
undetectable		 3kpdC-4f3sA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		3 / 3 TYR A  92
ASP A 196
ASP A 130
 None
 0.70A 3ou6B-4f3sA:
undetectable		 3ou6B-4f3sA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		3 / 3 TYR A 150
ASP A 166
ASP A 159
 None
 0.82A 3r24A-4f3sA:
undetectable		 3r24A-4f3sA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA214_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 10 VAL A  13
TYR A  42
PHE A  39
PHE A 202
ASN A 213
 None
 1.50A 3r6wA-4f3sA:
undetectable
3r6wB-4f3sA:
undetectable		 3r6wA-4f3sA:
22.10
3r6wB-4f3sA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A  13
ILE A 200
ILE A 227
SER A  41
LEU A  50
 None
 1.06A 4a84A-4f3sA:
undetectable		 4a84A-4f3sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		5 / 11 ILE A 170
ALA A 168
GLY A 121
GLY A 163
ASN A 162
 None
 1.10A 4e47C-4f3sA:
undetectable		 4e47C-4f3sA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		4 / 7 THR A  79
ASP A 130
GLY A 125
TYR A 122
 None
 0.97A 5hwaA-4f3sA:
undetectable		 5hwaA-4f3sA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4f3s PUTATIVE PERIPLASMIC
BINDING PROTEIN
(Salmonella
enterica) 		4 / 5 ASP A  35
ILE A  86
PHE A  88
TYR A  92
 None
 1.25A 6a93B-4f3sA:
undetectable		 6a93B-4f3sA:
20.90