SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		4 / 5 LEU A 251
ILE A   6
ALA A 244
MET A   4
 None
 1.04A 4dc3B-4f3yA:
5.2		 4dc3B-4f3yA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 12 ALA A 244
ALA A 247
ALA A 248
VAL A  94
LEU A  73
 None
 1.12A 4j6dA-4f3yA:
undetectable		 4j6dA-4f3yA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 12 TYR A 240
ALA A  22
ALA A 244
GLY A 243
LEU A 245
 None
 1.09A 4oaeA-4f3yA:
undetectable		 4oaeA-4f3yA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 9 ALA A  47
ALA A  11
LEU A  35
LEU A  24
VAL A  23
 None
 1.18A 4or0A-4f3yA:
undetectable		 4or0A-4f3yA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 9 ALA A  47
ALA A  11
LEU A  35
LEU A  24
VAL A  23
 None
 1.12A 4or0B-4f3yA:
undetectable		 4or0B-4f3yA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		4 / 6 GLU A 151
GLY A 204
ARG A 198
ARG A 181
 None
 1.48A 5jcnB-4f3yA:
4.3		 5jcnB-4f3yA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIH_A_8CVA201_1
(DIHYDROFOLATE
REDUCTASE)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		4 / 8 ILE A   6
ALA A  70
LEU A  96
ILE A   8
 None
 0.81A 5uihA-4f3yA:
2.0		 5uihA-4f3yA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 10 LEU A  35
LEU A  83
LEU A  90
ALA A  89
LEU A  96
 None
 0.99A 5y7pB-4f3yA:
undetectable		 5y7pB-4f3yA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 10 LEU A  35
LEU A  83
LEU A  90
ALA A  89
LEU A  96
 None
 1.02A 5y7pD-4f3yA:
undetectable		 5y7pD-4f3yA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 4f3y DIHYDRODIPICOLINATE
REDUCTASE
(Burkholderia
thailandensis) 		5 / 10 LEU A  35
LEU A  83
LEU A  90
ALA A  89
LEU A  96
 None
 1.05A 5y7pH-4f3yA:
undetectable		 5y7pH-4f3yA:
23.43