SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 6 LEU A 365
LEU A 368
LEU A 304
CYH A 235
 None
 0.77A 2ab2A-4f41A:
undetectable		 2ab2A-4f41A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 5 LEU A 365
LEU A 368
LEU A 304
CYH A 235
 None
 0.76A 2ab2B-4f41A:
undetectable		 2ab2B-4f41A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 6 VAL A 130
TYR A 176
GLU A 157
ILE A 160
 None
 1.15A 3q5sA-4f41A:
undetectable		 3q5sA-4f41A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 8 GLU A 358
GLU A 357
LEU A 219
TYR A 408
 None
 1.11A 3rqwF-4f41A:
undetectable
3rqwJ-4f41A:
undetectable		 3rqwF-4f41A:
21.49
3rqwJ-4f41A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		5 / 12 LEU A 342
GLY A 323
THR A 338
LEU A 242
GLY A 328
 None
 1.05A 3vaqB-4f41A:
undetectable		 3vaqB-4f41A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 8 LEU A 191
MET A 190
THR A 195
TYR A 176
 None
 1.17A 3wipF-4f41A:
undetectable
3wipJ-4f41A:
undetectable		 3wipF-4f41A:
21.02
3wipJ-4f41A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		3 / 3 TYR A 369
PHE A 265
ARG A 254
 None
 0.97A 4g19D-4f41A:
undetectable		 4g19D-4f41A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 6 GLU A 337
THR A 338
LEU A 341
GLN A 322
 None
 1.27A 4qztA-4f41A:
undetectable		 4qztA-4f41A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		3 / 3 MET A 150
HIS A 188
GLY A 143
 None
 0.84A 5gwzB-4f41A:
undetectable		 5gwzB-4f41A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		5 / 12 ARG A 254
VAL A 259
LEU A 317
GLU A 258
ALA A 263
 None
 1.06A 6f6iA-4f41A:
undetectable
6f6iB-4f41A:
1.1		 6f6iA-4f41A:
14.33
6f6iB-4f41A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		5 / 11 ILE A 279
LEU A 236
GLY A 245
PHE A 265
ALA A 263
 None
 1.04A 6ieyA-4f41A:
undetectable
6ieyB-4f41A:
undetectable		 6ieyA-4f41A:
21.47
6ieyB-4f41A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 4f41 PROTELOMERASE
(Agrobacterium
fabrum) 		4 / 7 GLY A 393
ASN A 396
GLU A 291
GLY A 290
 None
 0.88A 6n7fA-4f41A:
undetectable		 6n7fA-4f41A:
14.89