SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLY A 153
LEU A 128
VAL A  96
SER A 150
ALA A 151
 None
 1.15A 1dfoA-4f48A:
undetectable		 1dfoA-4f48A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLY A 153
LEU A 128
VAL A  96
SER A 150
ALA A 151
 None
 1.15A 1dfoB-4f48A:
undetectable		 1dfoB-4f48A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLY A 153
LEU A 128
VAL A  96
SER A 150
ALA A 151
 None
 1.15A 1dfoC-4f48A:
undetectable		 1dfoC-4f48A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		5 / 12 GLY A 153
LEU A 128
VAL A  96
SER A 150
ALA A 151
 None
 1.15A 1dfoD-4f48A:
undetectable		 1dfoD-4f48A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		5 / 12 MET A 108
PHE A  21
LEU A  82
LEU A  23
LEU A 128
 None
 1.41A 1eiiA-4f48A:
undetectable		 1eiiA-4f48A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		4 / 5 GLU A 159
THR A 213
LEU A 179
LEU A 181
 None
 1.22A 1u18B-4f48A:
undetectable		 1u18B-4f48A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		4 / 5 LEU A 181
ASP A 188
MET A 224
LEU A  31
 None
 1.27A 2jfaA-4f48A:
undetectable		 2jfaA-4f48A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		4 / 5 LEU A 181
ASP A 188
MET A 224
LEU A  31
 None
 1.27A 2qxsA-4f48A:
undetectable		 2qxsA-4f48A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		4 / 5 LEU A 181
ASP A 188
MET A 224
LEU A  31
 None
 1.28A 2qxsB-4f48A:
undetectable		 2qxsB-4f48A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		3 / 3 PHE A  42
TYR A  39
LEU A  45
 C2E  A 501 (-3.6A)
None
None
 0.70A 3keeB-4f48A:
undetectable		 3keeB-4f48A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		4 / 8 GLY A 120
GLN A  86
LEU A 116
ILE A  79
 None
 0.88A 3nbqB-4f48A:
undetectable		 3nbqB-4f48A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		3 / 3 PHE A  42
TYR A  39
LEU A  45
 C2E  A 501 (-3.6A)
None
None
 0.79A 3sueB-4f48A:
undetectable		 3sueB-4f48A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		3 / 3 TYR A  39
HIS A  90
ARG A  85
 None
 0.78A 4htfA-4f48A:
undetectable		 4htfA-4f48A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		3 / 3 LEU A 212
ASP A 233
TYR A 234
 None
 0.67A 4qc6B-4f48A:
undetectable		 4qc6B-4f48A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		4 / 8 LEU A 181
ILE A 199
ALA A 230
PRO A 176
 None
 0.79A 5m0oC-4f48A:
undetectable		 5m0oC-4f48A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		5 / 12 LEU A  31
PHE A 227
VAL A 235
ALA A 241
GLY A 237
 None
 1.07A 5tzoB-4f48A:
undetectable		 5tzoB-4f48A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		3 / 3 TYR A  39
ALA A 241
LEU A 246
 None
 0.65A 6d9kF-4f48A:
undetectable		 6d9kF-4f48A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4f48 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Xanthomonas
campestris) 		6 / 10 ILE A 211
VAL A 135
ALA A 142
LEU A 158
LEU A 171
LEU A 170
 None
 1.34A 6f6nA-4f48A:
undetectable
6f6nB-4f48A:
undetectable		 6f6nA-4f48A:
15.60
6f6nB-4f48A:
15.51