SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f54'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 4f54 UNCHARACTERIZED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 VAL A 144
TYR A 140
GLU A 156
ILE A 154
 None
 1.23A 3q5sA-4f54A:
undetectable		 3q5sA-4f54A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 4f54 UNCHARACTERIZED
PROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A  42
ASP A  44
PHE A  45
VAL A 173
 None
MLY  A  43 ( 4.7A)
MLY  A 161 ( 4.9A)
None
 1.14A 5a1rA-4f54A:
undetectable		 5a1rA-4f54A:
17.05