SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		6 / 11 SER A  79
LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.72A 1rqjA-4f62A:
34.0		 1rqjA-4f62A:
46.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		6 / 11 SER A  79
LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.93A 1rqjA-4f62A:
34.0		 1rqjA-4f62A:
46.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		6 / 11 SER A  79
LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.70A 1rqjB-4f62A:
33.9		 1rqjB-4f62A:
46.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		6 / 11 SER A  79
LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.92A 1rqjB-4f62A:
33.9		 1rqjB-4f62A:
46.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.88A 1yhlA-4f62A:
24.0		 1yhlA-4f62A:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.07A 1yhlA-4f62A:
24.0		 1yhlA-4f62A:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.74A 1yv5A-4f62A:
23.4		 1yv5A-4f62A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.98A 1yv5A-4f62A:
23.4		 1yv5A-4f62A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A 214
GLY A 213
MET A 174
HIS A  76
ILE A  46
 None
None
None
GOL  A 402 (-4.4A)
GOL  A 402 (-4.3A)
 1.38A 1z95A-4f62A:
undetectable		 1z95A-4f62A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 ALA A 211
ALA A 267
GLN A 270
ALA A 207
ILE A  46
 None
None
None
None
GOL  A 402 (-4.3A)
 1.14A 2aclC-4f62A:
4.1		 2aclC-4f62A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.44A 2eimW-4f62A:
undetectable		 2eimW-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.83A 2f8cF-4f62A:
24.3		 2f8cF-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.04A 2f8cF-4f62A:
24.3		 2f8cF-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.79A 2f8zF-4f62A:
24.2		 2f8zF-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.01A 2f8zF-4f62A:
24.2		 2f8zF-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.73A 2f94F-4f62A:
24.1		 2f94F-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.87A 2f9kF-4f62A:
24.0		 2f9kF-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.04A 2f9kF-4f62A:
24.0		 2f9kF-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 THR A 194
GLY A  59
LEU A  57
ALA A 191
LEU A 192
 None
 1.08A 2npnA-4f62A:
undetectable		 2npnA-4f62A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.85A 2o1oA-4f62A:
22.9		 2o1oA-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.04A 2o1oA-4f62A:
22.9		 2o1oA-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		3 / 3 LEU A 281
PRO A 280
LEU A 284
 None
 0.57A 2po7B-4f62A:
undetectable		 2po7B-4f62A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 ALA A 185
GLY A 180
GLY A 213
LEU A  72
ILE A  46
 None
None
None
None
GOL  A 402 (-4.3A)
 0.90A 2z0yA-4f62A:
undetectable		 2z0yA-4f62A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.32A 3ag1J-4f62A:
undetectable		 3ag1J-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.42A 3ag2J-4f62A:
undetectable		 3ag2J-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.26A 3ag4J-4f62A:
undetectable		 3ag4J-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		3 / 3 ARG A  13
VAL A  58
THR A 194
 None
 0.65A 3cyxA-4f62A:
undetectable		 3cyxA-4f62A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.87A 3ez3D-4f62A:
23.3		 3ez3D-4f62A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.06A 3ez3D-4f62A:
23.3		 3ez3D-4f62A:
25.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.85A 3n45F-4f62A:
24.1		 3n45F-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.04A 3n45F-4f62A:
24.1		 3n45F-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.86A 3n46F-4f62A:
23.9		 3n46F-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.06A 3n46F-4f62A:
23.9		 3n46F-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		3 / 3 LYS A 257
LEU A 253
ALA A 256
 None
 0.68A 4ikiA-4f62A:
undetectable		 4ikiA-4f62A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.79A 4kpdA-4f62A:
24.0		 4kpdA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.98A 4kpdA-4f62A:
24.0		 4kpdA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.83A 4kpjA-4f62A:
23.5		 4kpjA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.88A 4kq5A-4f62A:
23.8		 4kq5A-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.01A 4kq5A-4f62A:
23.8		 4kq5A-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.81A 4kqsA-4f62A:
23.8		 4kqsA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.01A 4kqsA-4f62A:
23.8		 4kqsA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 ALA A  53
GLN A   5
PHE A   6
TYR A   9
THR A  10
 None
 1.35A 4ltwA-4f62A:
undetectable		 4ltwA-4f62A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.79A 4nkeA-4f62A:
23.7		 4nkeA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.00A 4nkeA-4f62A:
23.7		 4nkeA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.87A 4nkfA-4f62A:
24.0		 4nkfA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.81A 4nuaA-4f62A:
23.8		 4nuaA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.00A 4nuaA-4f62A:
23.8		 4nuaA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 9 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.88A 4oguA-4f62A:
23.5		 4oguA-4f62A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A 214
GLY A 213
MET A 174
HIS A  76
ILE A  46
 None
None
None
GOL  A 402 (-4.4A)
GOL  A 402 (-4.3A)
 1.37A 4okbA-4f62A:
3.1		 4okbA-4f62A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.89A 4p0wA-4f62A:
23.9		 4p0wA-4f62A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 11 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.03A 4p0wA-4f62A:
23.9		 4p0wA-4f62A:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.78A 4rxdA-4f62A:
10.6		 4rxdA-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.98A 4rxdA-4f62A:
10.6		 4rxdA-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.78A 4rxdB-4f62A:
23.7		 4rxdB-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.97A 4rxdB-4f62A:
23.7		 4rxdB-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.77A 4rxdC-4f62A:
23.7		 4rxdC-4f62A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 10 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.96A 4rxdC-4f62A:
23.7		 4rxdC-4f62A:
25.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		6 / 8 SER A  79
LEU A  80
ASP A  83
ASP A  89
MET A 151
LYS A 178
 None
 0.59A 4umjA-4f62A:
37.1		 4umjA-4f62A:
50.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 8 SER A  79
LEU A  80
ASP A  83
GLN A 155
LYS A 178
 None
 1.21A 4umjA-4f62A:
37.1		 4umjA-4f62A:
50.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		7 / 9 SER A  79
LEU A  80
ASP A  83
ASP A  89
MET A 151
LYS A 178
THR A 179
 None
 0.53A 4umjB-4f62A:
37.4		 4umjB-4f62A:
50.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		6 / 9 SER A  79
LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.02A 4umjB-4f62A:
37.4		 4umjB-4f62A:
50.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 THR A 118
LEU A 116
ALA A 115
LEU A 111
LEU A  31
 None
 0.93A 4xi3C-4f62A:
undetectable		 4xi3C-4f62A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 6 HIS A  76
GLY A  43
GLU A  73
ARG A  45
 GOL  A 402 (-4.4A)
GOL  A 402 (-3.6A)
GOL  A 402 ( 4.8A)
None
 1.04A 4zbqA-4f62A:
3.6		 4zbqA-4f62A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 6 LYS A 277
ASP A 283
TYR A 208
LEU A 205
 None
 1.37A 5bmvB-4f62A:
undetectable		 5bmvB-4f62A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.81A 5cg5A-4f62A:
23.4		 5cg5A-4f62A:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 1.01A 5cg5A-4f62A:
23.4		 5cg5A-4f62A:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A  80
ASP A  83
ASP A  89
LYS A 178
THR A 179
 None
 0.79A 5cg6A-4f62A:
24.1		 5cg6A-4f62A:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		5 / 12 LEU A  80
ASP A  83
GLN A 155
LYS A 178
THR A 179
 None
 0.99A 5cg6A-4f62A:
24.1		 5cg6A-4f62A:
27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 4 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.42A 5wauj-4f62A:
0.0		 5wauj-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.08A 5x19J-4f62A:
undetectable		 5x19J-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.16A 5x1bJ-4f62A:
undetectable		 5x1bJ-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.30A 5x1bW-4f62A:
undetectable		 5x1bW-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.38A 5x1fW-4f62A:
undetectable		 5x1fW-4f62A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 8 ILE A 152
GLN A 155
GLU A 162
SER A 160
 None
 1.08A 6c06C-4f62A:
undetectable		 6c06C-4f62A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f62 GERANYLTRANSTRANSFER
ASE
(Marinomonas
sp.
MED121) 		4 / 5 TYR A  17
ARG A  13
THR A  65
LEU A  64
 None
 1.28A 6nknJ-4f62A:
undetectable		 6nknJ-4f62A:
10.09