SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 TYR A 308
GLN A 396
THR A 359
SER A 263
 None
 1.44A 1eiiA-4f7aA:
undetectable		 1eiiA-4f7aA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 ILE A 455
VAL A 296
ARG A 304
LEU A 406
ASP A 302
 None
 1.26A 1nb9A-4f7aA:
undetectable		 1nb9A-4f7aA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 THR A 432
ILE A 455
VAL A 296
ARG A 304
ASP A 302
 None
 1.16A 1nb9A-4f7aA:
undetectable		 1nb9A-4f7aA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 GLU A 149
THR A 359
ILE A 269
TYR A 274
 None
 1.07A 1qvtA-4f7aA:
undetectable		 1qvtA-4f7aA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 146
GLN A  55
VAL A 208
THR A 130
ILE A 129
 None
 1.20A 1z95A-4f7aA:
undetectable		 1z95A-4f7aA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 300
ALA A 294
SER A 295
GLY A 290
TRP A 458
 None
 1.00A 2igtA-4f7aA:
undetectable		 2igtA-4f7aA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 300
ALA A 294
SER A 295
GLY A 290
TRP A 458
 None
 0.98A 2igtB-4f7aA:
undetectable		 2igtB-4f7aA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 300
ALA A 294
SER A 295
GLY A 290
TRP A 458
 None
 1.00A 2igtC-4f7aA:
undetectable		 2igtC-4f7aA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_D_SC2D1290_1
(FICOLIN-2)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 GLY A  85
TRP A 454
TRP A 465
LEU A 476
 None
 1.37A 2j2pD-4f7aA:
undetectable
2j2pF-4f7aA:
undetectable		 2j2pD-4f7aA:
17.99
2j2pF-4f7aA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 TYR A 116
PHE A 120
ASP A 175
TYR A 163
 GOL  A 601 ( 3.9A)
None
None
None
 1.48A 2todA-4f7aA:
undetectable
2todB-4f7aA:
undetectable		 2todA-4f7aA:
20.77
2todB-4f7aA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 181
LEU A 358
GLU A 149
ARG A 232
ALA A 234
 None
 1.46A 3apvA-4f7aA:
undetectable		 3apvA-4f7aA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 THR A 451
PHE A 365
ARG A 304
ALA A 402
TYR A 386
 None
 1.29A 3apxA-4f7aA:
undetectable		 3apxA-4f7aA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 ILE A 293
GLY A 290
GLY A 323
LEU A 322
ILE A 305
 None
 1.07A 3em4V-4f7aA:
undetectable		 3em4V-4f7aA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLU A 387
GLY A 389
PHE A 394
ALA A 456
GLN A 452
 None
 1.10A 3nvkF-4f7aA:
undetectable
3nvkJ-4f7aA:
undetectable		 3nvkF-4f7aA:
21.91
3nvkJ-4f7aA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLU A 387
TYR A 405
PHE A 394
ALA A 456
GLN A 452
 None
 1.16A 3nvkF-4f7aA:
undetectable
3nvkJ-4f7aA:
undetectable		 3nvkF-4f7aA:
21.91
3nvkJ-4f7aA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 ILE A 267
TRP A 458
ILE A 455
TRP A 397
 None
 1.13A 3weoA-4f7aA:
undetectable		 3weoA-4f7aA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 VAL A 192
TYR A 140
ILE A 223
ILE A 145
 None
 0.96A 4afgD-4f7aA:
undetectable
4afgE-4f7aA:
undetectable		 4afgD-4f7aA:
16.44
4afgE-4f7aA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 PHE A 139
TYR A 136
THR A  49
ILE A 211
 None
 1.18A 4jx1E-4f7aA:
undetectable		 4jx1E-4f7aA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 THR A  99
GLY A 327
GLY A  85
PHE A  83
GLY A 290
 None
 1.19A 4kqiA-4f7aA:
undetectable		 4kqiA-4f7aA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 ASP A  89
VAL A 100
ASN A  77
 None
 0.81A 4lmnA-4f7aA:
undetectable		 4lmnA-4f7aA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TRP A 107
GLN A 501
THR A 108
 None
 1.00A 4m2xA-4f7aA:
undetectable		 4m2xA-4f7aA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 146
GLN A  55
VAL A 208
THR A 130
ILE A 129
 None
 1.25A 4okbA-4f7aA:
undetectable		 4okbA-4f7aA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 LEU A 146
GLN A  55
VAL A 208
THR A 130
ILE A 129
 None
 1.21A 4okwA-4f7aA:
undetectable		 4okwA-4f7aA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 ARG A 304
ALA A 399
ASP A 302
SER A 263
 None
 1.13A 4ot2A-4f7aA:
undetectable		 4ot2A-4f7aA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_B_SAMB603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 PHE A 499
ASP A 503
GLN A 510
VAL A 174
ILE A 154
 None
GOL  A 601 ( 2.8A)
GOL  A 601 (-3.4A)
None
None
 1.42A 4pcuA-4f7aA:
undetectable
4pcuB-4f7aA:
undetectable		 4pcuA-4f7aA:
23.32
4pcuB-4f7aA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 PHE A 499
ASP A 503
GLN A 510
VAL A 174
ILE A 154
 None
GOL  A 601 ( 2.8A)
GOL  A 601 (-3.4A)
None
None
 1.40A 4uuuA-4f7aA:
undetectable
4uuuB-4f7aA:
undetectable		 4uuuA-4f7aA:
13.76
4uuuB-4f7aA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 198
TYR A 136
SER A 220
ALA A 226
ALA A 191
 None
 1.49A 4ymgA-4f7aA:
undetectable		 4ymgA-4f7aA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLY A 421
ILE A 494
TYR A 101
GLY A  85
THR A 292
 None
 1.23A 5eslA-4f7aA:
0.0		 5eslA-4f7aA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 LEU A 476
THR A 292
PRO A 474
LEU A 297
 None
 1.03A 5fxtA-4f7aA:
undetectable		 5fxtA-4f7aA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ILE A 375
GLY A 374
SER A 371
ALA A 370
ALA A 249
 None
 1.16A 5n0oB-4f7aA:
undetectable		 5n0oB-4f7aA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 VAL A 390
GLY A 389
ASP A 401
ALA A 402
LEU A 406
 None
 1.06A 5x6yB-4f7aA:
undetectable		 5x6yB-4f7aA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 HIS A  80
ASN A  79
LEU A  78
 None
 0.90A 6f7lB-4f7aA:
undetectable		 6f7lB-4f7aA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 VAL A 390
ALA A 402
GLN A 452
 None
 0.67A 6gb9A-4f7aA:
undetectable		 6gb9A-4f7aA:
21.63