SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 4f7c CD1D ANTIGEN, D
POLYPEPTIDE
(Bos
taurus) 		3 / 3 TRP A 277
ALA A 252
VAL A 256
 None
 0.70A 1c4dC-4f7cA:
undetectable
1c4dD-4f7cA:
undetectable		 1c4dC-4f7cA:
5.43
1c4dD-4f7cA:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 4f7c CD1D ANTIGEN, D
POLYPEPTIDE
(Bos
taurus) 		3 / 3 ALA A 252
VAL A 256
TRP A 277
 None
 0.74A 1tkqB-4f7cA:
undetectable		 1tkqB-4f7cA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 4f7c CD1D ANTIGEN, D
POLYPEPTIDE
(Bos
taurus) 		4 / 6 ILE A  81
PRO A 138
LEU A 124
ILE A 141
 0SG  A 306 ( 4.7A)
None
0SG  A 306 ( 4.8A)
None
 0.96A 2q83B-4f7cA:
undetectable		 2q83B-4f7cA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 4f7c CD1D ANTIGEN, D
POLYPEPTIDE
(Bos
taurus) 		5 / 10 LEU A  66
ILE A 165
PRO A  37
VAL A 173
GLY A  56
 None
 1.50A 2qd4B-4f7cA:
undetectable		 2qd4B-4f7cA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 4f7c CD1D ANTIGEN, D
POLYPEPTIDE
(Bos
taurus) 		5 / 12 SER A  16
ILE A  96
GLY A 120
VAL A 123
ALA A 137
 None
0SG  A 306 ( 4.2A)
None
None
None
 1.18A 4foxD-4f7cA:
undetectable		 4foxD-4f7cA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 4f7c CD1D ANTIGEN, D
POLYPEPTIDE
(Bos
taurus) 		4 / 6 TRP A  63
GLY A  56
THR A  57
VAL A 173
 None
 1.11A 5ewuB-4f7cA:
undetectable		 5ewuB-4f7cA:
23.04