SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4f7g TALIN-1
(Mus
musculus) 		5 / 10 VAL B1706
LEU B1741
LEU B1814
THR B1812
THR B1813
 None
 1.30A 1rj6A-4f7gB:
undetectable		 1rj6A-4f7gB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4f7g TALIN-1
(Mus
musculus) 		5 / 10 VAL B1706
LEU B1741
LEU B1814
THR B1812
THR B1813
 None
 1.19A 1rj6B-4f7gB:
undetectable		 1rj6B-4f7gB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 4f7g TALIN-1
(Mus
musculus) 		5 / 12 ALA B1719
VAL B1807
ILE B1709
MET B1803
THR B1804
 None
 1.13A 3czhA-4f7gB:
undetectable		 3czhA-4f7gB:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 4f7g TALIN-1
(Mus
musculus) 		5 / 12 ALA B1719
VAL B1807
ILE B1709
MET B1803
THR B1804
 None
 1.15A 3czhB-4f7gB:
undetectable		 3czhB-4f7gB:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 4f7g TALIN-1
(Mus
musculus) 		4 / 7 ALA A 360
SER A 365
THR A 367
SER A 379
 None
 0.46A 4iklA-4f7gA:
undetectable
4iklB-4f7gA:
undetectable		 4iklA-4f7gA:
22.17
4iklB-4f7gA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 4f7g TALIN-1
(Mus
musculus) 		4 / 8 SER A 379
ALA A 360
SER A 365
THR A 367
 None
 0.45A 4iklA-4f7gA:
undetectable
4iklB-4f7gA:
undetectable		 4iklA-4f7gA:
22.17
4iklB-4f7gA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4f7g TALIN-1
(Mus
musculus) 		3 / 3 PRO A 267
LEU A 266
GLN A 273
 None
 0.70A 4pevB-4f7gA:
undetectable		 4pevB-4f7gA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 4f7g TALIN-1
(Mus
musculus) 		3 / 3 HIS A 255
LYS A 254
PHE A 259
 None
 1.43A 5klaA-4f7gA:
undetectable		 5klaA-4f7gA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4f7g TALIN-1
(Mus
musculus) 		5 / 12 TYR B1777
VAL B1807
THR B1811
PHE B1738
LEU B1668
 None
 1.36A 6a93B-4f7gB:
2.3		 6a93B-4f7gB:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 4f7g TALIN-1
(Mus
musculus) 		5 / 11 GLU B1770
SER B1679
ALA B1678
THR B1752
ALA B1817
 None
 1.27A 6efnA-4f7gB:
undetectable		 6efnA-4f7gB:
19.42